1 July

Efferalgan - instruction , application reviews

Contents:

1. active substance

2. Product form

3. Composition

4. Indications

5. Contraindications

6. dosage and Administration

7. Side effects

8. Cautions

9. Terms and Conditions of storage

Efferalgan - analgesic, antipyretic drug.

active substance

Acetaminophen (Paracetamol).

Product form

Efferalgan comes in the form of rectal suppositories, syrup, effervescent tablets and tablets with vitamin C.

syrup sold in bottles of polietilenftalata (volume 90 mL) in a cardboard package (1 fl. Each).It comes with measuring spoon.

rectal suppositories are available in blisters (5 supp. Each), placed in cardboard boxes with 2 pieces.

Effervescent tablets are produced in strips (Table 4. Each) and cartons of 4 or 25 strips.

effervescent vitamin C tablets sold in tubes (Table 10. Each) in packs of cartons one piece.

Composition

syrup (for children), 3%

100 ml

Paracetamol

30 mg

Excipients: sugar syrup(water, sucrose), macrogol 6000,

potassium sorbate, sodium saccharin, citric acid, purified water, caramel-vanilla flavor.

Rectal Suppositories

1 supp.

Paracetamol

80 mg

150 mg 300 mg

Excipients: semisynthetic glycerides.

effervescent tablets

Table 1.

Paracetamol

500 mg

Excipients: sodium carbonate anhydrous, anhydrous citric acid, sorbitol, sodium bicarbonate, sodium docusate, sodium benzoate, povidone, soluble saccharin.

effervescent tablets with vitamin C

Table 1.

Paracetamol

Ascorbic acid

330 mg

200 mg

Excipients: sodium bicarbonate, sodium benzoate, potassium bicarbonate, anhydrous citric acid, sorbitol, povidone, sodium docusate.

Indications

Efferalgan appointed in the following cases:

  • As analgesic drug in pain syndrome of moderate or low intensity (including dental, migraine and headaches, neuralgia, sore throat, back pain, musclethe pain of burns and injuries, painful menstruation).
  • as an antipyretic agent in children's infections, influenza, acute respiratory diseases, postprivivochnyh reactions and other infectious and inflammatory diseases against which the body temperature rises.

Contraindications Contraindications to receive Efferalgan in the form of syrup and suppositories are:

  • blood diseases.
  • Severe functional disorders of the kidneys and liver.
  • recent bleeding or inflammation of the rectum (contraindication due to the route of administration - a suppository).
  • Lack of the enzyme glucose-6-phosphate dehydrogenase.
  • Children under the age of 3 months (suppository 80 mg), 1 month (syrup).
  • Hypersensitivity to paracetamol.

contraindication to receiving Efferalgan in the form of effervescent tablets are:

  • The lack of glucose-6-phosphate dehydrogenase.
  • Alcoholism.
  • Children under the age of 15 years (body weight - not less than 50 kg).
  • period of pregnancy (I and III trimester) and breastfeeding (lactation).
  • Individual hypersensitivity to paracetamol or other auxiliary components of the drug.

drug is given with extreme caution: the liver and / or kidney failure, viral hepatitis, congenital hyperbilirubinemia (Rotor syndrome, Dubinin-Johnson and Gilbert), alcoholic liver disease, as well as elderly patients.

contraindication to receiving Efferalgan in the form of tablets with vitamin C are:

  • Children under 8 years old.
  • Hypersensitivity to paracetamol and other components of the preparation.

Efferalgan taken with extreme caution: benign hyperbilirubinemia (including Gilbert's syndrome), hepatic and renal failure, alcoholic liver disease, viral hepatitis, alcoholism, old age, pregnancy, breast-feeding (lactation), deficiency of glucose-6-phosphate dehydrogenase.

Dosing and Dosage

syrup is administered orally as after dilution (juice, milk or water) and in pure form.

average single dose calculated from the child's body weight, and usually about 10-15 mg / kg 3-4 times per day.The maximum daily dose should not exceed 60 mg / kg.Break between meals Efferalgan should be 4-6 hours.For precision dosing should use the measuring spoon, which marked the division corresponding to the weight of the baby's body.

  • child with a body weight from 4 to 16 kg : dial syrup in a measuring spoon to the level corresponding to its body weight or to the level that is closest in value to the weight of the baby.
  • child body weight 16 to 32 kg : dial syrup scoop to the level of 10 kg, and then again - as long as the total amount of drug will match the patient's body weight.

Duration of treatment - 5 days as an analgesic and 3 days as antipyretic.If necessary, a longer dosing should consult a specialist.

Suppositories are for rectal use.After removing the candles from the packaging it is necessary to enter into the anus baby (preferably after a spontaneous bowel movement or enema).

average single dose of the drug based on their body weight, and usually about 10-15 mg / kg 3-4 times per day.The maximum daily dose should not exceed 60 mg / kg.

  • Children from 3 to 5 months (6-8 kg body weight) - 1 suppository (80 mg).
  • Children from 6 months to 3 years old (with a weight of 10-14 kg body ) - 1 suppository (150 mg).
  • children from 5 to 10 years old (weighing 20-30 kg) - 1 suppository (300 mg), 3-4 times a day with intervals of 4-6 hours.

Do not use more than 4 candles a day.When using Efferalgan more than a week is required to monitor the pattern of peripheral blood and functional state of the liver.

tablets are taken orally, dissolved in 200 ml drinking water.Typically prescribed to 1 - 2 tablets.2-3 times a day at intervals not less than 4 hours.The maximum single dose - 2 tab.(1 g), day - Table 8.(4 g).

patients with functional disorders of the kidneys or liver, and in elderly patients Efferalgan interval between doses should be at least 8 hours and the daily dose should be reduced.Duration of treatment is the same as in the previous cases.

Efferalgan with vitamin C taken orally.Before you take a pill it must be dissolved in a glass of water (200 mL).

Children average single dose of effervescent tablets with vitamin C is selected depending on body weight and is 10-15 mg paracetamol per 1 kg 3-4 times a day.The maximum daily dose should not exceed 60 mg / kg.

Efferalgan Dosage depends on body weight and age of the child is presented in the following table.

child's body weight, kg

Age Child, years

number of tablets at a time

maximum number of tablets per day

25-33

8-12

1

3-4

33-50

12-15

1.5

4-6

Babiesover 15 years (with a body weight of 50 kg or more), as well as the adult prescribe: Table 2-3.2-3 times per day.The maximum single dose - Table 3.(990 mg paracetamol).The maximum daily dose - 12 Table.(3960 mg paracetamol).

break between the individual doses Efferalgan must be at least 4 hours.In patients with functional disorders of the kidneys or liver, with Gilbert's syndrome and in elderly patients the interval between doses tablets must be at least 8 hours.The daily dose should be reduced.

Side effects

common to all dosage forms : in some cases, possible nausea, vomiting, irritation of the rectum, allergic reactions (urticaria, pruritus, angioedema, skin rash);rarely - thrombocytopenia, leukopenia, anemia, methemoglobinemia, neutropenia.With prolonged use at high doses there is a risk of nephrotoxicity and hepatotoxicity.

Additionally syrup : may be abdominal pain, diarrhea, decreased blood pressure (as a sign of anaphylaxis), allergic reactions (anaphylaxis), increase or decrease in prothrombin index.

Additionally, for effervescent tablets : with long-term use at doses higher than recommended, increasing the likelihood of functional disorders of the kidney and liver (requires monitoring of peripheral blood picture).

Additionally, for effervescent tablets with vitamin C:

  • central and peripheral nervous system : agitation, dizziness and disorientation (usually appears at high doses).
  • Gastrointestinal : gepatonekroz (dose-dependent effect), epigastric pain, nausea, increase in liver transaminases, usually without jaundice.
  • Urinary system (with high doses): nephrotoxicity (nonspecific bacteriuria, renal colic, papillary necrosis, interstitial nephritis).
  • Skin : rash on the mucous membranes and skin (usually urticaria or erythematous), pruritus, angioedema, Lyell's syndrome (toxic epidermal necrolysis), erythema multiforme exudative (including Stevens-Johnson syndrome).
  • Endocrine system: hypoglycemia, up to the development of hypoglycemic coma.
  • Agencies hematopoiesis : methemoglobinemia (heart pain, shortness of breath), sulfogemoglobinemiya, hemolytic anemia (especially for patients with a lack of glucose-6-phosphate dehydrogenase), anemia (cyanosis).

Cautions

common to all dosage forms: using the drug longer than 5-7 days it takes control of the functional state of the liver and peripheral blood picture.

Additionally, for effervescent tablets: to prevent liver toxicity drug should not be combined with the consumption of alcoholic beverages, as well as use in patients who are prone to continuous reception of alcohol.

The composition of one tablet Efferalgan includes 412.4 mg of sodium, which should take into account patients who are on a strict diet low in salt.Due to the fact that the formulation contains sorbitol, it is not recommended to use in poor absorption of glucose and galactose, fructose intolerance, isomaltase deficiency.

Additionally, for effervescent tablets with vitamin C: due to the stimulating effect of ascorbic acid on the production of corticosteroid hormones, required to monitor the blood pressure and renal function.With prolonged use of high doses of vitamin C there is a risk of oppression works insular apparatus of the pancreas.

Patients with a high content of iron in the body to be taken ascorbic acid in minimal doses.Appointment of medications, which include ascorbic acid, in patients with metastatic intensively and rapidly growing malignant tumors may increase during the process.

Ascorbic acid may distort the results of the various laboratory tests (transaminases, lactate dehydrogenase, bilirubin in the blood).

One effervescent tablet contains vitamin C with 330 mg of sodium, which should be considered patients that conform to the low-salt diet.

General for effervescent tablets and tablets with vitamin C: risk of liver damage increases in patients with alcoholic gepatozom.Pri long-term use of the drug required to control the functional state of the liver and peripheral blood picture.

Additionally syrup: in sostavpreparata include paracetamol, so to avoid exceeding the maximum daily dose should not be used concurrently with other Efferalgan preparations containing this substance.

In the case of dosing children who are on a diet low in sugar or diabetes mellitus, must take into account that 1 ml of syrup contains 0.335 grams of sugar.

Conditions and terms

Keep out of direct sunlight at a temperature not exceeding 30 ° C.Keep away from children.Shelf life - 3 years.

Attention!

Product description posted on this page is a supplement and a simplified version of the official version of the annotations to the drug.The information is provided for informational purposes only and is not a guide to self-medication.Before using the product you should consult with a specialist and to get acquainted with the instructions approved by the manufacturer.

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