1. active substance
2. Product form
6. dosage and Administration
7. Side effects
9. Terms and Conditions of storage
Fluorouracil-LENS - uracil antimetabolite having anticancer activity.
The drug is available as a solution for intracavitary and intravascular injection of 250 mg / 5 ml.The solution is implemented in ampoules 5 ml each, into cartons (10, 25, 35 and 50 vials each).
Fluorouracil-LENS is assigned to the following pathological conditions:
Contraindications Contraindications to the use of the drug:
With extreme caution Fluorouracil-LENS is prescribed for acute infectious diseases of bacterial, fungal and viral etiology (including tuberculosis, herpes zoster, chickenpox), infiltration of the tumor of the bone marrow cells before chemotherapy or radiation therapy, as well as athepatic and renal failure.
Fluorouracil is included in the composition of many chemotherapy regimens, so when choosing a dose and mode of administration in each individual case should be guided by the special literature.The drug is administered intravenously, intraarterially, intracisternally and by slow infusion.
Recommended doses and regimens:
application of fluorouracil-LENS can cause the development of the following adverse reactions:
Since Fluorouracil-LENS is a cytostatic, then you must treat it with extreme caution.
If you have diarrhea or stomatitis therapy should be discontinued until symptoms data.
Patients previously treated with alkylating drugs or exposed to large doses of radiation during treatment must be careful.
The initial dose should be reduced by 30-50% in the following situations: post-operative period less than 30 days after the complicated surgery, weight loss, disruption of the kidney and liver, impaired bone marrow function.
Men and women of childbearing age during treatment, as well as after it (for 3 months) should use reliable contraceptives.
During therapy need to regularly inspect the oral cavity of the patient to identify stomatitis, determine hemoglobin, hematocrit, bilirubin level and the activity of liver function tests, as well as control the number of white blood cells, platelet count and absolute neutrophil count.
Side effects provoked by the use of fluorouracil-LENS, may adversely affect the performance of work requiring speed of psychomotor reactions, and road management capabilities.
Store in a dark and protected from children, at a temperature range - from 15 to 25 ° C.Shelf life - 2 years.
Product description posted on this page is a supplement and a simplified version of the official version of the annotations to the drug.The information is provided for informational purposes only and is not a guide to self-medication.Before using the product you should consult with a specialist and to get acquainted with the instructions approved by the manufacturer.
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