26 June

Fenilin - instruction , application reviews

Contents:

1. Pharmacological action

2. Instructions for use fenilina

3. fenilina contraindications and side effects

drug Fenilin is a medication for thewhich prevents blood clotting.

Produced Fenilin spigot in the form of tablets of white or light beige.

The main active ingredient is the active substance fenilina phenindione.Each tablet contains 0.03 g fenilina phenindione, and various auxiliary substances: citric acid, starch, milk sugar, talc.

for various indications can be assigned fenilina counterparts.The main counterparts fenilina include medicated preparations: Trombantin, phenindione, Danilo, Atrombon, Trombozol, Dindevan, Emandion, Diofindan, Gedulin, Pindion, Fenilindandion, Tromazal, Trombofen, Trombotil.

Pharmacological action

The instructions for use fenilina reported that the drug belongs to the group of indirect anticoagulants (drugs that slow the process of blood clotting).Phenindione structure, the main active ingredient fenilina does not coincide with the st

ructure of the product group 4-oksikumarina, but the mechanisms of action of these two substances are very similar to each other.Phenindione can cause hypoprothrombinemia (reduction in blood prothrombin concentration - important clotting factor), which is broken when prothrombin synthesis in the liver and decreased synthesis of coagulation factors of blood (VII, IX, X).

Within 8-10 hours after receipt of the body fenilina a reduction in the concentration of clotting factors, and after 24-30 hours the maximum effect.

Instructions for use fenilina

The instructions to fenilina reported that the drug should be used to reduce blood clotting.More often than not assigned to use this drug for the treatment and prevention of thrombosis.For the treatment of thrombosis should take Fenilin for a long time.

also instructions for fenilina reported that the drug can be used for the treatment and prevention of the following diseases:

  • thrombophlebitis (vein occlusion, occurs as a result of inflammation of the walls of veins);
  • thromboembolism (blockage of the vascular lumen of blood clot);
  • myocardial infarction;
  • embolic stroke (blockage of the blood vessels of the brain caused by acute cerebrovascular accident);
  • embolic lesion (blockage of a foreign agent of the vessel or blood clot).

The instructions for use fenilina reported that the drug can be used in surgical practice in the postoperative period to prevent the development of various complications.

not assigned Fenilin in hemorrhagic stroke (cerebral vascular rupture, provoked acute cerebrovascular accident).

Fenilin often appointed as an adjunct in the treatment of heparin.

fenilina The instructions to the prescribed dosage of the drug following:

  • In most cases, the first day of treatment Fenilin taken at a dose of 0,12-0,18 g per day (total daily dose is divided into 3-4 receptions).On the second day of treatment in the dosage adopted Fenilin 0,09-0,15 g per day, but on subsequent days - in a dosage of 0.03-0.06 g per day (the dosage may be adjusted depending on the prothrombin concentration in the blood).The maximum permitted daily dose of the drug for adults - 0.2 g, and the highest single dose - 0.05 g Indicator coagulation operation called prothrombin index, should be maintained during the course of treatment at the level of 40-50%.
  • To prevent clogging of blood vessels by blood clots (prevention of thromboembolic complications) Fenilin take 1-2 times a day at a dose of 0.03-0.06
  • In acute thrombosis conduct a comprehensive treatment of heparin and fenilina.

Numerous reviews of fenilina report on the effectiveness of this drug.

During treatment fenilina necessary to conduct systematic studies of the blood levels of various coagulation factors (prothrombin, etc.), therefore treatment with this drug is conducted under strict medical supervision.

fenilina contraindications and side effects of the drug is contraindicated

Fenilin in the following cases:

  • if you are hypersensitive fenilina components;
  • with original content prothrombin of less than 70%;
  • in various diseases that are associated with reduced blood clotting (hemorrhagic diathesis, etc.);
  • with increased vascular permeability;
  • pregnant and lactating women;
  • in renal / liver function;
  • with pericarditis;
  • of malignancy;
  • ulcers of the gastrointestinal tract.

left untreated fenilina during menstrual bleeding, as well as in the first week after birth.

extremely carefully carried fenilina treatment of elderly patients.

reviews fenilina reported that in most cases the drug is well tolerated by patients.However, some reviews about fenilina report on the possibility of the development of the drug on a background of the following side effects: headache, allergic reactions, diarrhea, bleeding.

fenilina Overdose can lead to various complications, such as bleeding, caused by increased permeability of the capillaries, micro- and gross hematuria (blood in the urine excretion), gastric and intestinal bleeding, bleeding from the nose or mouth, bleeding into muscles, etc..

When bleeding treatment fenilina stopped and immediately administered vitamin K, ascorbic acid, vitamin P products, calcium chloride, as well as carry out a transfusion hemostatic doses (80 ml) fresh blood unicast.

should also be extremely cautious Fenilin used in combination with other medical drugs.Please be aware that the anticoagulants of indirect action, and in particular Fenilin, enhance the effect of difenina, butamida and glucocorticoids.

Attention!

Product description posted on this page is a supplement and a simplified version of the official version of the annotations to the drug.The information is provided for informational purposes only and is not a guide to self-medication.Before using the product you should consult with a specialist and to get acquainted with the instructions approved by the manufacturer.

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