12 August

Tranexam - instruction , application reviews

Contents:

1. composition and the form of Traneksama

2. Pharmacological action

3. Indications Traneksama

4. Contraindications

5. Dosing Traneksama

6. Side effects Traneksama

7. storage conditions and shelf-life of the drug

Tranexam is a drug that belongs to a group of hemostatic agents.This medication has a good local and systemic hemostatic effects.Suitable cure for bleeding of various origins, some allergic diseases, hereditary angioedema and inflammatory ailments of the mouth.

composition and the form of Traneksama

According to the instructions, Tranexam comes in the form of ampoule solution for intravenous injection and tablets, film-coated.

One tablet contains 500 mg composed of tranexamic acid and excipients such as calcium stearate, giproloza, microcrystalline cellulose, talc, carboxymethyl starch and silicon dioxide colloidal.The composition of the shell comprises: macrogol, titanium dioxide, talc and hypromellose.Implement Tranexam tablets in blisters (10

pieces each), placed in cardboard boxes.

Tranexam One milliliter of solution contains 50 mg of tranexamic acid, and water for injection.Implement solution in 5 ml ampoules, placed into cardboard boxes (10 vials each).

Pharmacological action

Tranexam - fibrinolysis inhibitor.This medication has antifibrinolytic effect and prevents the conversion of plasminogen to plasmin.Judging by the reviews, Tranexam has good local and systemic hemostatic effects.Its use is particularly effectively for bleeding, which are accompanied by a high content of fibrinolizina in the blood, for example, with menorrhagia or platelet pathology.In addition, the analyzed drug has antiallergic, antiinflammatory and antitumor activity.

Tranexam very well distributed in all tissues of the human body, and can even penetrate through the placenta and the blood-brain barrier.After application of tablets Tranexam maximum concentration of active substance in the blood observed after three hours.In the tissues of the therapeutic concentration is approximately seventeen hours.

Indications Traneksama

solution and tablets Tranexam apply in the following situations:

  • treatment and prevention of bleeding provoked by local activation fibrinolizina: hematuria, uterine and nasal bleeding, gastrointestinal bleeding, extraction of teeth in patients with hemorrhagic diathesis;
  • prevention and treatment of bleeding due to increased system maintenance fibrinolizina: liver disease, bleeding during pregnancy, cancer of the pancreas and prostate, postpartum bleeding, manual removal of the placenta, placental chorionic, hemophilia, leukemia, as well as the operation and early postoperative period;
  • hereditary angioedema;
  • inflammatory diseases of the oral cavity: stomatitis, laryngitis, pharyngitis, tonsillitis, aphthae mucous layer of the mouth;
  • allergic diseases: toxic and drug rash, allergic dermatitis, eczema and hives.

Contraindications

Tranexam, in the opinion of medical experts, can not be used in such pathological conditions as:

  • subarachnoid hemorrhage;
  • hypersensitivity to the active substance or auxiliary components of the drug.

With caution is prescribed solution and tablets Tranexam at:

  • trombogemorragicheskih complications (in combination with indirect anticoagulants and heparin);
  • thrombosis (thrombophlebitis, myocardial infarction, cerebral thrombosis) or the threat of their occurrence;
  • renal failure;
  • haematuria from the upper urinary tract;
  • violation of color vision.

Using the above medication during pregnancy is permissible only in cases where use of the drug for the mother of the body is much higher than the probability of a possible negative impact on the fetus.

contraindicated Tranexam combined with blood, penicillin, hypertensive agents, tetracyclines, urokinase and diazepam.

Dosing Traneksama

According to the instructions, in the form of Tranexam intravenous solution used to stop bleeding, which arose at the time of surgery, as well as massive bleeding.After tooth extraction, in patients with impaired blood clotting medication is also administered intravenously.After extraction, usually Tranexam prescribed in tablet form.

Tranexam tablets are:

  • When uterine bleeding - 1 g four times a day for three days.
  • In the postoperative period - 1.5 g three times a day for ten to fourteen days.
  • After tooth extraction in patients with hemorrhagic diathesis - 25 mg / kg four times a day for a week.
  • When recurring nosebleeds - 1 g three times a day for seven days.
  • therapy for hereditary angioedema Tranexam assigned courses or continuously 1 g twice a day.

Side effects Traneksama

On reviews, Tranexam may provoke the following side effects:

  • allergic reactions: itching, skin rash, and urticaria;
  • the central nervous system: a violation of color vision, drowsiness, and dizziness;
  • of the digestive system: diarrhea, heartburn, nausea, loss of appetite and vomiting;
  • by blood coagulation thrombosis and thromboembolism;
  • Other: tachycardia, and pain in the chest area.

Judging by the reviews, Tranexam at very rapid introduction leads to the development of arterial hypotension.

storage conditions and shelf-life of the drug

Keep the medicine must be analyzed in a dry, protected from light and the reach of children at a temperature not exceeding 30 degrees Celsius.

Traneksama Shelf life is three years from the date of issue.

Attention!

Product description posted on this page is a supplement and a simplified version of the official version of the annotations to the drug.The information is provided for informational purposes only and is not a guide to self-medication.Before using the product you should consult with a specialist and to get acquainted with the instructions approved by the manufacturer.

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