1. active substance
2. Product form
6. dosage and Administration
7. Side effects
9. Terms and Conditions of storage
Seretide - beta adrenomimeticheskoe, anti-asthmatic, glucocorticoid, an anti-inflammatory,bronchodilatory drug.
fluticasone + Salmeterol (Fluticasone + Salmeterol).
Seretide is available in the form of metered aerosol for inhalation.The preparation is realized in aluminum inhalers (for 120 doses) complete with a plastic spray.
(in terms of salmeterol 25g)
125 mcg to 250 mcg
Seretide for a regular treatment of asthma if the patient shows the combined treatment with inhaled corticosteroids and beta2-agonists long-term exposure:
Seretide for maintenance therapy in patients with chronic obstructive pulmonary disease (COPD) with a forced inspiratory volume value & lt;60% of predicted values, and repeated exacerbations in history, despite regular treatment with bronchodilators.
contraindications to the drug is:
Take Seretide, like other inhalants, which include corticosteroids, should be with caution in patients with latent or acute pulmonary tuberculosis.
Also, this drug should be used with caution in hyperthyroidism, fungal, bacterial or viral infections of the respiratory system.
Any inhaled corticosteroids (including Seretide) can cause systemic effects, especially with prolonged use at high doses.Therefore, the drug should be used with caution in osteoporosis, cataracts, glaucoma.
When receiving sympathomimetic medicines group, especially in exceeding therapeutic doses, the risk of developing certain cardiovascular events (eg, increase in heart rate and systolic blood pressure).For this reason, it is recommended Seretide used with caution in people with cardiovascular disease, including ventricular premature beats, supraventricular tachycardia and extrasystoles, atrial fibrillation.
There are reports of increased blood glucose levels, so patients with diabetes should be used with caution Seretide.
all sympathomimetic drugs at doses exceeding therapeutic, may trigger a transient decrease in potassium in the blood serum.Therefore Seretide should be administered with caution to patients with hypokalemia.
drug is intended only for inhalation.
Determination of duration of treatment and the dose change is possible only by Medicine specialist recommendations.
The patient should be informed that in order to achieve optimal effect Seretide must be taken regularly, even if clinical symptoms of COPD and asthma are absent.
doctor should regularly review the effectiveness of treatment of the patient.
In bronchial asthma Seretide is assigned to the following recommended doses:
Data on the use of the drug in children under 4 years are not available at the moment.
dose of the drug is required to drop to the lowest ensuring effective control of the disease symptoms.If reception
medicament two times a day provides the control features within the reduction to the minimum effective dose, frequency of administration Seretide can be reduced to 1 times daily.
When COPD is the maximum recommended dose for adults is two inhalations (250 mcg fluticasone propionate and 25 mcg salmeterol) 2 times a day.
In elderly patients and in patients with functional disorders of the liver or kidney is not necessary to reduce the dose of Seretide.
Instructions for use of the inhaler
1. Remove the mouthpiece cap, slightly squeeze the sides.
2. Inspect the unit from inside and outside, including the mouthpiece for the presence of foreign objects.
3. Shake the inhaler and release a jet into the air.This helps ensure that the extraneous elements are removed and that the contents of the device is evenly distributed.
4. Hold the inhaler upside down, in the upright position.Hold the device between the thumb and the other fingers of the hand.It is necessary that the thumb placed on the basis of a mouthpiece.
5. Exhale with maximum force.Place the mouthpiece in your mouth, tightly clasping his lips (no biting).
6. Making a deep, slow breath through your mouth, press gently on the top of the inhaler to spray the drug.
7. holding the breath (as possible), remove your finger from the top of the device and remove the inhaler from the mouth.
8. To make a second spraying hold the inhaler upright and repeat steps 3-7 after 30 seconds.
9. After using the inhaler, rinse your mouth with water and then spit it.
10. Click on the mouthpiece cap and snap it into position.If it clicks happens, gently rotate the mouthpiece cap and try to close it again.Do not press the cap firmly.
The drug can also be used through a spacer.
In the first few times it is desirable to practice in front of a mirror.If during the procedure of the corners of the mouth and the upper part of the inhaler out "fog", then you have to do it all over again, starting from step 2.
If your doctor has given you other instructions on the use of the inhaler, try to strictly observe them.In case of difficulty with using the device, please contact your doctor.
Since young children can not independently use an inhaler, they need adult support.Wait until the baby breathe out, and since the beginning of the inhalation device to bring the action.Practice in the use of an inhaler with the child.Older children and adults with weak hands should hold the inhaler with both hands.Thus thumbs should be based on the lower die, and the index - on top of the device.
inhaler Clean the inhaler is required at least once a week.This is done as follows:
1. Remove the mouthpiece cap.
2. The metal canister should not be removed from the plastic casing.
3. cotton swab or dry cloth to wipe the outside and inside the mouthpiece and the plastic casing - outside only.
4. Close the protective cap mouthpiece.
immersed in water a metal spray is prohibited.
drug Seretide contains salmeterol and fluticasone propionate, and therefore it is expected that it can cause side effects that are typical of these components.
Data from clinical studies:
postmarketing observational data:
Overdose symptoms: tremor, tachycardia, and headache.When fluticasone propionate is used in doses higher than recommended, it can cause depression of the hypothalamic-pituitary-adrenal axis (time).Typically, this condition does not require urgent action, as in most cases of adrenal function is restored a few days.
Bronchial asthma is recommended to treat stages, overseeing the lung function of the patient and the clinical response to therapy.The patient should be taught to use the inhaler correctly.
Seretide is not intended to relieve acute symptoms of the disease, since in such cases it is necessary to use a fast-acting inhaled bronchodilator (eg, salbutamol).Patients should be informed that they are always at hand there was a drug for relief of acute symptoms.
Fluticasone propionate / salmeterol can be used for the initial maintenance therapy in patients with persistent asthma when indicated to receive corticosteroids and in determining their dosages.
more frequent use of bronchodilators to relieve short-exposure signs indicating a worsening disease control in such situations, the patient should contact the doctor.
Because of the risk of exacerbation of therapy with Seretide should not be abruptly stop.The dose of the drug is recommended to be reduced gradually under the supervision of a specialist.
children receiving prolonged treatment with inhaled corticosteroids is recommended to regularly measure the growth.
In patients with hypoxia and exacerbation of asthma is required to control the concentration of K + in plasma.
There are reports of an increase in blood glucose concentration, and this should be remembered by assigning a combination of fluticasone propionate with salmeterol in patients with diabetes mellitus.
Keep out of direct sunlight at a temperature not exceeding +30 ° C.
Keep away from children.
Shelf life - 2 years.
Product description posted on this page is a supplement and a simplified version of the official version of the annotations to the drug.The information is provided for informational purposes only and is not a guide to self-medication.Before using the product you should consult with a specialist and to get acquainted with the instructions approved by the manufacturer.
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