1. Pharmacological properties and indications for use
2. Instructions for Remeron
3. contraindications and side effects of Remeron
Remeron - a drug group tetracyclic antidepressants.The active ingredient of Remeron is mirtazapine.Means produced in the form of tablets, film-coated.One tablet contains 30 mg of Remeron mirtazapine.
Remeron has a strong sedative (calming) effect.The mechanism of drug action based on its ability to enhance central noradrenergic and serotonergic neurotransmission and inhibit alpha-2 adrenoceptors in the central nervous system.
As the reviews of Remeron as well as relevant studies, the drug exhibits the highest efficiency in the treatment of depression, accompanied by daily fluctuations of mood, sleep disturbances, inability to experience joy and pleasure, psychomotor retardation, loss of interest, weight loss and suicidal thoughts.
reviews Remeron indicate that the maximu
tablets should be taken orally, without chewing and drinking plenty of fluids.Typically, the drug is prescribed for one admission per day.Remeron is desirable to take before bedtime.Also, the doctor may prescribe means for fractional doses which provide reception means morning and evening.
Remeron initial dose for adults and elderly patients is 15 mg per day.Further dose increases to achieve the desired therapeutic effect.The optimal dose is determined individually and can range from 15 to 45 mg per day.
In the absence of improvement after the first 2-4 weeks of treatment, the dose of Remeron increase, but if improvements did not occur at the end of the next 2-4 weeks, the therapy is stopped.In the case of a good patient's response to drug treatment is continued for 4-6 months until complete elimination of the clinical manifestations of depression.
According to the instructions, Remeron is contraindicated in case of hypersensitivity, and for the treatment of children under 18 years.The drug is not indicated for patients with lactase deficiency, lactose intolerance, as well as a syndrome of glucose-galactose malabsorption.
Remeron during pregnancy may be imposed only in those cases where a doctor has reason to believe that the benefits of treatment to the mother outweighs the potential risk to the fetus.In the drug is not indicated during lactation, as data about his ability to stand together with the breast milk is not available.
As indicated in the instruction, Remeron (when used in therapeutic doses) has virtually no effect on the cardiovascular system.Furthermore, unlike other antidepressants, this means almost no anticholinergic effects.However, the drug still has a number of negative impacts.
Remeron reviews indicate that most side effects are manifested in the form of drowsiness, confusion, tremor, myoclonus.In rare cases, the use of Remeron may experience delusions, seizures, skin reactions.Also, in some cases receiving Remeron is able to provoke weight gain, fluid retention, and increased activity of plasma transaminases.
Sometimes the use of the drug leads to the oppression of blood, namely the development of eosinophilia, orthostatic hypotension, agranulocytosis, granulocytopenia, thrombocytopenia, or aplastic anemia.It is noteworthy that these side effects often occur at 4-6 week therapy.After completion of treatment data negative manifestations, as a rule, do not require further treatment and tested independently.
Remeron is not indicated in combination with MAO inhibitors, including within two weeks after discontinuation of these drugs.
If signs of jaundice Remeron therapy should be discontinued immediately.In case of any signs of infection such as sore throat, fever or disease, Remeron cancel and appointed CBC.
With special care agent is used to treat patients with organic brain damage and epilepsy, because Remeron can cause them to seizures.In addition, the drug is prescribed with caution in patients with the following diseases and disorders:
Remeron in the treatment of patients with schizophrenia may increase psychotic symptoms.When using Remeron in the treatment of the depressive phase of bipolar disorder can develop mania.
should know that the sudden discontinuation of the drug may cause headache, nausea, and a general deterioration of health.
During therapy, patients should refrain from drinking alcohol, driving a vehicle, and the performance of potentially hazardous activities.Women while taking Remeron must use reliable contraception.
Product description posted on this page is a supplement and a simplified version of the official version of the annotations to the drug.The information is provided for informational purposes only and is not a guide to self-medication.Before using the product you should consult with a specialist and to get acquainted with the instructions approved by the manufacturer.
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