Polkortolon - instruction , application reviews

Contents:

1. active substance

2. Product form

3. Composition

4. Indications

5. Contraindications

6. dosage and Administration

7. Side effects

8. Cautions

9. Conditions and terms

Polkortolon - synthetic glucocorticosteroid with a strong anti-inflammatory effect.

active substance

Triamcinolone (Triamcinilone)

Product form

drug is released in the form of round, flat tablets of white color, with chasing "4 / mg" on one side and an "O" - on the other.

tablets sold in blister packs of 25 pieces in cardboard packs, 2 blisters in each.

Composition

1 tab.

triamcinolone

4 mg

Excipients: magnesium stearate, potato starch, lactose.

Indications

Indications for use Polkortolona are the following pathological conditions:

  • Hard occurring allergic diseases that are resistant to other methods of treatment (atopic dermatitis, contact dermatitis, drug allergy, serum sickness, seasonal or perennial allergicrhinitis).
  • Endocrine diseases (congenital adrenal hyperplasia, primary and secondary adrenocortical insufficiency, subacute thyroiditis).
  • Rheumatic diseases (rheumatic myocarditis, acute rheumatic fever, juvenile rheumatoid arthritis, rheumatoid arthritis, Horton's disease, polymyalgia rheumatica).
  • Diseases of the musculoskeletal system (ankylosing spondylitis, epicondylitis, acute and subacute bursitis, post-traumatic osteoarthritis, acute tenosynovitis).
  • hematologic disease (congenital aplastic anemia, acquired autoimmune hemolytic anemia, anemia, bone marrow hypoplasia provoked, secondary thrombocytopenia in adults, thrombocytopenic purpura disease in adults, hemolysis).
  • Dermatological diseases (bullous dermatitis herpetiformis, severe erythema multiforme, pemphigus, severe eczema, exfoliative dermatitis, severe seborrheic dermatitis, mycosis fungoides, severe psoriasis, pemphigoid).
  • Neurological diseases (multiple sclerosis during exacerbation, tuberculous meningitis with subarachnoid block, as well as the threat of its occurrence).
  • Respiratory diseases (berylliosis, severe bronchial asthma, symptomatic sarcoidosis, aspiration pneumonitis, Loeffler's syndrome, disseminated or fulminant pulmonary tuberculosis).
  • Severe chronic and acute inflammatory diseases of the eye (sympathetic ophthalmia, optic neuritis, severe sluggish posterior and anterior uveitis).
  • liver disease (chronic active hepatitis, alcoholic hepatitis with encephalopathy).
  • Oncological diseases (acute leukemia in children with lymphoma and leukemia in adults).
  • hypercalcemia, provoked malignant neoplasms.

Also, the drug is prescribed for treatment and prevention of graft rejection during transplantation of tissues and organs.

Contraindications

Polkortolon contraindicated in the following situations:

  • Systemic fungal infections.
  • Individual intolerance to the active substance or auxiliary components of the drug.
  • Children under 3 years old.

wary drug prescribed for infectious and parasitic diseases of bacterial, fungal and viral (herpes zoster, herpes simplex, measles, chicken pox, strongyloidiasis, amoebiasis, latent and active tuberculosis, systemic mycosis).Use in severe infections is permitted only against the background of a specific treatment.

Caution should be observed in such diseases of the gastrointestinal tract, such as: gastritis, esophagitis, peptic ulcer disease 12 duodenal ulcer and stomach, ulcerative colitis, with the threat of abscess formation or perforation, latent or acute peptic ulcer, diverticulitis, bowel anastomosis (the newly created).

wary drug prescribed for immunodeficiency (HIV, AIDS), lymphadenitis after BCG vaccination, as well as in the post-vaccination period.

Caution should be observed in patients suffering from cardiovascular diseases (recent myocardial infarction, hyperlipidemia, hypertension, chronic decompensated heart failure).

With extreme caution when the drug is prescribed endocrine diseases (diabetes, Cushing's disease, hypothyroidism), severe chronic renal and hepatic failure, hypoalbuminemia, nefrourolitiaze, myasthenia gravis, systemic osteoporosis, zakryto- and open-angle glaucoma, polio, obesity 3-4degree, acute psychosis, as well as during pregnancy and lactation.

Dosage and Administration

dose and duration of treatment is determined by the doctor individually, depending on the condition of the patient, indications and efficacy.

daily dose taken once - in the morning, during breakfast.In some situations, take medication more often.

Adults and children over 14 years Polkortolon appoint 4-48 mg per day.Babies drug is given in a daily dose of 100-500 mg / kg body weight.

In the case of missed tablets medication must be taken as soon as possible.Missed dose is not taken only when approaching the next reception.A double dose taken once forbidden.

Polkortolon usually administered in a minimum effective dose, which can be gradually reduced if necessary.

Side effects

use of the drug may cause the following side effects:

  • Digestive system: erosive esophagitis, steroid ulcer 12 duodenal ulcer and stomach, bloating, nausea, vomiting, pancreatitis, hiccups, a decrease or increase in appetite, disturbancedigestion, increase in liver enzymes.
  • Endocrine System: Cushing's syndrome (obesity, pituitary type, moon face, high blood pressure, hirsutism, striae, myasthenia gravis, dysmenorrhea, amenorrhea), secondary hypothalamic-pituitary and adrenal insufficiency, suppression of growth and delayed sexual development in children, impaired glucose tolerance, menstrual disorders, hirsutism, manifestation of latent diabetes mellitus, increased need for oral hypoglycemic agents or insulin in patients with diabetes mellitus.
  • central and peripheral nervous system: disorientation, delirium, hallucinations, euphoria, paranoia, depression, manic depression, increased intracranial pressure, pseudotumor cerebellum, vertigo, headache, dizziness, sleep disturbance, anxiety or nervousness, convulsions.
  • Musculoskeletal system: slowing bone growth and ossification processes, osteoporosis, muscle tendon rupture, steroid myopathy, muscle weakness, loss of muscle mass.
  • bodies of: increased intraocular pressure, glaucoma, posterior subcapsular cataracts, exophthalmos, trophic changes of the cornea, the tendency to the development of secondary fungal, viral and bacterial infections of the eyes.
  • Dermatological reactions: slow wound healing, striae, steroid acne, petechiae, thinning of the skin, a tendency to the development of pyoderma and candidiasis, hematoma, ecchymosis.
  • Metabolism: hyperglycemia, negative nitrogen balance, glycosuria, hypocalcemia, increased excretion of calcium, sweating, weight gain, fluid retention and sodium in the body, hypokalemic syndrome (hypokalemia, muscle spasm or myalgia, fatigue, unusual weakness,arrhythmia), hypernatremia.
  • Allergic reactions: pruritus, rash, anaphylactic shock.
  • Other: leucocyturia, withdrawal, development or exacerbation of infection.

severity and frequency of side effects depend on the used dose and duration of use.At short-term use of triamcinolone side effects are rare.Application

drug in high doses may cause undesirable reactions such as peripheral edema, increased blood pressure, as well as strengthening the above side effects.

overdose treatment involves the gradual abolition of the drug or dose reduction and symptomatic therapy.

Cautions

In the event of stress patients taking Polkortolon require parenteral administration of glucocorticosteroids.

Abrupt withdrawal of the drug can trigger the development of adrenal insufficiency.

triamcinolone may mask the symptoms of infections, as well as to reduce resistance to infectious diseases, and the ability to limit their development.Prolonged use of the analyzed glucocorticosteroid increases the likelihood of secondary viral and fungal infections, causes the development of cataracts and glaucoma with damage to the optic nerves.

Patients taking Polkortolon, vaccinate live virus vaccines can not.In the treatment of glucocorticosteroid risk of neurological complications increases after vaccination.

With the sudden cancellation of the drug, especially after a long course of therapy, may develop "cancellation" syndrome, which is characterized by fever, anorexia, general weakness, joint and muscle pains.

During treatment patients may experience mental disorders (insomnia, euphoria, symptoms of psychosis, severe depression, personality changes, mood changes).Existed earlier psychotic tendencies and emotional instability during therapy may increase.

People suffering gipoprotrombinemiey should be combined with caution triamcinolone and acetylsalicylic acid.

in pediatric patients with prolonged use Polkortolona requires regular monitoring of children's growth and development.

Conditions and terms

Store in a dry, dark and protected from children, at room temperature not exceeding 25 ° C.Shelf life - 3 years from the date of issue.

Attention!

Product description posted on this page is a supplement and a simplified version of the official version of the annotations to the drug.The information is provided for informational purposes only and is not a guide to self-medication.Before using the product you should consult with a specialist and to get acquainted with the instructions approved by the manufacturer.

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