1. structure and pharmacological action
2. Instruction Penesteru - indications for use
3. Further guidance on the application of Penestera
Asreported data of medical statistics, over 50% of men who have attained the age of 51-60 years have histologic benign prostatic hyperplasia (BPH), and men over 80 years suffer from this disease in 90% of cases.Almost half of the cases the disease is asymptomatic and not too worried about the stronger sex.However, 75% pyatidesyatipyatiletnih half semidesyatipyatiletnih men symptoms will occur and require adequate treatment.
Benign prostatic hyperplasia is essentially a non-cancerous enlarged prostate.This ailment has nothing to do with prostate cancer.It is believed that almost every man in the elderly faced with the development of BPH and the disease, unfortunately, is an integral part of the normal aging process.Do not shy away from this disease, and men who have observed the normal functioning of the testes and prostate.Contribute
Among the main symptoms of this disorder include: a weak urine stream, straining to urinate, feeling nedoopustosheniya bladder pressure during voiding.Immediately seek medical help in cases where there is one of the following symptoms: urinary retention (inability to urinate), blood in the urine, urinary tract infection, difficulty in urinating, urinary incontinence.
Pleases the fact that in many cases excellent results giving medication."The gold standard" in the treatment of BPH is still a transurethral resection of the prostate.Also, in some cases, it is assigned only dynamic monitoring of disease or surgical intervention.The drug therapy is often used an effective drug for the treatment of BPH - Penester.
Penester is produced in the form of light yellow, biconvex tablets coated with a thin film coating.Penestera One tablet contains 5 mg of active ingredient - finasteride and excipients: magnesium stearate, iron oxide yellow, dimethicone emulsion SE2, lactose monohydrate, povidone 30, carboxymethylstarch sodium, docusate sodium, corn starch, talc, titanium dioxide.In each blister pack comprises 10 or 15 pieces of tablets.Effective
finasteride active substance is a synthetic 4-azasteroid compounds, and is a specific competitive inhibitor of the intracellular enzyme steroid 5-alpha reductase, which is capable of converting testosterone to DHT, 5-active androgen DHT.After all, at the expense occurring in the cells of the prostate gland transformation of testosterone into dihydrotestosterone begins the development of benign prostatic hyperplasia and activates the growth of prostate tissue.Contained in Penestere finasteride significantly reduces digidrosterona level in prostate tissue and in plasma.This Finasteride does not come into contact with the androgen receptor.In therapy Penesterom marked decrease prostate size, decrease the severity of symptoms caused by benign prostatic hyperplasia.It should be noted that the medical preparation has no effect on plasma lipid levels, and does not alter the concentration of thyroxine, cortisol, prolactin, thyroid-stimulating hormone and estradiol in the blood plasma.
Penester after ingestion is absorbed rather quickly from the region of the gastrointestinal tract.Is drug, regardless of the meal, bioavailability is approximately 80%.After 1-2 hours after administration of the drug inside reached its maximum concentration in the plasma.Finasteride is displayed in the form of metabolites in the faeces and urine and is metabolized by the liver.In patients older than 60 years half-life of the drug is 6 hours, and in patients older than 70 years - 8 hours.
According to the instructions Penesteru, this drug is indicated for the treatment of benign prostatic hyperplasia.Positive reviews about Penestere confirm the effectiveness of this drug.Also reviews of Penestere reported that the use of the drug leads to a reduction in the size of the prostate, subsiding the symptoms of the disease, normalization of urine expiration rate and reduce the risk of acute urinary retention, in which quite often resort to surgical treatment.
a day, eating food intake of the drug does not affect The instructions to Penesteru recommended to take the drug inside of 1 tablet (5 mg).The recommended duration of therapy should be at least 6 months, after which the doctor assesses the effectiveness of the prescribed treatment, and provides further guidance.Almost 50% of the patients disappeared clinical symptoms of the disease after undergoing a 12-month treatment Penesterom.
The instructions to Penesteru prescribed contraindications to the use of this drug.It is contraindicated in case of hypersensitivity to finasteride and other ingredients.Prohibited purpose of this drug for prostate cancer, as well as urinary tract obstruction.Do not assigned the drug and patients younger than 18 years.With extreme caution applies Penester with abnormal liver function.
Separate reviews of Penestere reported various side effects caused by the use of this drug.Perhaps the development of allergic reactions, impotence, gynecomastia, can also feel breast tenderness, reduced ejaculate volume and decrease libido.The few reviews about Penestere report on the possibility of increasing to 10% the level of follicle-stimulating and luteinizing hormone and testosterone, but these figures do not exceed the limits of normal values.In the treatment of reduced incidence of side effects.
cases of drug overdose Penester is not known, also were not conducted clinical studies on the interaction of the drug with other medicines.
Before transgress to medication Penesterom, you must make sure that there are no diseases, stimulate benign prostatic hyperplasia.Such infectious diseases include prostate, urethral stricture, prostate cancer, bladder hypotension and various changes in the urinary system caused by certain diseases of the nervous system.
from time to time in the course of therapy, the patient should be screened for prostate cancer as well as in the application of finasteride marked decrease in prostate-specific antigen.
Product description posted on this page is a supplement and a simplified version of the official version of the annotations to the drug.The information is provided for informational purposes only and is not a guide to self-medication.Before using the product you should consult with a specialist and to get acquainted with the instructions approved by the manufacturer.
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