Metacin - instruction , application reviews

Metacin is a drug used to treat spasms. Metacin is a drug that helps to reduce the tone of internal organs, as well as to reduce the secretion of secretion by sweat, bronchial glands and glands of the gastrointestinal tract. In addition, this tool provides an improvement in the conductivity of AV, and also increases the frequency of cardiac contractions.

Metacin, in contrast to Atropine, has a more moderate effect. However, the symptoms manifested during the use of these drugs, such as increased intraocular pressure, paralysis of accommodation and dilated pupils, are less pronounced.


The drug is a blocker of m-holinoretseptorov, monochetvertichnoe connection. Metacin has a predominant effect on peripheral m-cholinergic receptors. Thus, this drug helps to reduce the tone of the smooth muscles of internal organs, as well as reduce the secretion of glands of the gastrointestinal tract, sweat and bronchial glands. The use of this agent provides an increase in heart rate, and also imp

roves AV-conduction. It should also be noted that Metacin does not have a central effect.


This product is available in the form of tablets, as well as in the form of an injection solution.

In this case, one mg of metocinium iodide is contained in one ampoule of the injection solution. The solution is sold in cardboard packages, ten ampoules each.

One tablet contains 2 mg methocinium iodide. In this case, the tablets are sold in packs, ten tablets each.

Indications Metazin

According to the instructions of Metacin, this drug is used to eliminate spasms of the muscles of the internal organs, chronic gastritis, during the treatment of ulcers of the gastrointestinal tract, as well as in the presence of renal, hepatic and biliary colic.

In addition, Metacin is effective enough for the hypersecretion of the salivary and bronchial glands. It should be noted that Metacin is widely used in pregnancy: this drug helps to relax the muscles of the uterus, and also prevents the onset of premature birth and reduces the risk of miscarriage.

Methacine is also used in the process of pre-medication preparation of patients before surgery to reduce the salivary and bronchial glands.

Contraindications Metaxin

Usage Metazin is contraindicated if the patient has an individual hypersensitivity to one or more of the components that make up the product.

The Metacin instruction states that the drug should be taken with extreme caution in the presence of the patient's heart disease, hernia aperture oesophageal, elevated body temperature, reflux esophagitis, as well as gastrointestinal tract diseases characterized by obstruction.

In addition, this tool should not be taken with paralytic intestinal obstruction, intestinal atony in patients in advanced age and in weakened patients, diseases with intraocular hypertension, renal and hepatic insufficiency, ulcerative nonspecific colitis, chronic lung diseases( mainly in young children and weakenedpatients), autonomic neuropathy, myasthenia gravis, as well as urinary retention or predisposition to it.

Metazine is also contraindicated in gestosis, prostatic hypertrophy, not complicated by obstruction of the urinary tract, central paralysis and cerebral pathologies in children, as well as diseases of Down and tachycardia.

Instruction Metasin: method of application

According to the instructions of Metacin, this agent in the form of tablets should be applied two to three times a day to 0.002-0.004 g. The drug in the form of a solution of 0.1% is prescribed, usually in a dosage of 0.5-2 ml. In this case, the solution must be administered parenterally, i.e. intramuscularly, intravenously or subcutaneously.

The maximum permissible single dose of the drug for internal administration for adult patients is 0.005 g. The maximum allowable daily dose of Metazin is 0.015 g. For parenteral administration of the drug, the single dose is 0.002 g. The maximum allowable daily dose of this agent for parenteral administration is 0.006 g.

Methacine during pregnancy in the face of the threat of disruption should be taken daily from one to three tablets. Given the absence of a threat of miscarriage, this drug can be taken to eliminate irregular, minor pain that occurs during an attack. Necessary dosage Metacin in pregnancy should be determined directly by the doctor in charge.

Side effects of

In some cases, the use of Metacin can cause constipation, tachycardia, dry mouth, dilated pupils, thirst, urinary retention, dysphagia, accommodation paralysis, and increased intraocular pressure.

In case of an overdose, this medication appears at risk of atrial fibrillation.

In order to eliminate unwanted symptoms of an overdose, it is recommended to take anticholinesterase drugs.

Interaction Metasina with other drugs

An intensification of the anticholinergic effect is noted when concurrent use of Metasin with m-holinoblokatorami, as well as means characterized by anticholinergic activity.

Storage conditions and shelf life

The drug should be stored in a dark place at a temperature of no more than 20 ° C.If the required storage conditions are met, the expiration date will be three years.


1. Pharmacodynamics

2. Form

3. Indications for use Metazina

4. Contraindications for use Metasina

5. Instruction Metasin: method of application

6. Side effects of

7. InteractionMetazine with other medicinal products

8. Storage conditions and expiration date


Description of the drug, placed on this page, is a supplemented and simplified version of the official version of the annotation to the drug. The information is provided for informational purposes only and is not a guide for self-treatment. Before using the drug, you should consult a specialist and read the instructions approved by the manufacturer.

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