Kremgen - instruction , application reviews


1. Pharmacological action Kremgena

2. Instruction Kremgenu: indications for use

3. reviews Kremgene: side effects

4. Contraindicationsointments Kremgen and overdose

5. Additionally

Kremgen is a combination drug that is designed exclusively for external use.

The preparation includes an antibacterial agent from the group of aminoglycosides - gentamicin and fluocinonide, is a synthetic glucocorticosteroid 3 generations.

Pharmacological action Kremgena

fluocinonide has a pronounced anti-inflammatory, antiekssudativnoe, antiallergic and antipruritic effect.It is characterized by a membrane stabilizing effect with respect to the lysosomes and their ability to inhibit phospholipase A2, which leads to a reduction of cytokines and inflammatory mediators.Thus, fluocinonide tends to inhibit the release of inflammatory mediators and release cytokines by lymphocytes and macrophages.When used topically Kremgena fluocinonide in a short time it turns into a volatile compound,

enhancing and potentiating its anti-allergic and anti-inflammatory effect.

second active ingredient of the drug - Gentamicin is characterized by the ability to bind to ribosomes of bacteria, inhibiting protein synthesis.In addition, it is fixed on the cytoplasmic membrane, breaking thus its permeability.These processes influence the bacterial cells, which leads to a loss of amino acids, potassium ions and nucleotides.Gentamicin exerts its activity against microorganisms such as:

  • Staphulococcus aureus;
  • Proteus vulgaris;
  • Streptococcus spp .;
  • Pseudomonas aeruginosa;
  • Escherichia coli;
  • Shigella spp;
  • Acinetobacter spp .;
  • Enterobacter spp .;
  • Klebsiella pneumonia;
  • Salmonella spp.

In the case of local drug use of its components do not inhibit the activity of the adrenal cortex and are characterized by a pronounced influence of the system.Penetrating through the layers of inflamed, erosive or burnt skin, they have a therapeutic effect.

Kremgen manufacturer produces in the form of an ointment in tubes with a capacity of 15 and '30

The preparation includes the following components:

  • fluocinonide (0.05 g);
  • gentamicin sulfate (0.1 g);
  • polyethylene glycol 4000;
  • propylene glycol;
  • dimethicone;
  • citric acid;
  • stearyl alcohol;
  • glycerol.

Instruction Kremgenu: indications for use

Kremgen ointment is prescribed for the treatment of inflammatory and allergic diseases of the skin, particularly complicated by bacterial infection:

  • allergic dermatitis;
  • neurodermatitis;
  • eczema (including microbial, nummular eczema for the skin);
  • atopic dermatitis;
  • psoriasis;
  • contact allergic dermatitis;
  • abrasions;
  • folliculitis;
  • dermatitis (seborrhea, exfoliative, intertriginous, radiation).

Kremgen is also used in the treatment of skin diseases such as:

  • discoid lupus erythematosus;
  • senile and anogenital pruritus;
  • lichen planus;
  • trophic ulcers;

Also, the drug is used for burns 1st degree, frostbite and insect bites.

According to the instructions, Kremgen recommended 2-3 times a day, causing a thin layer to the affected areas of skin inflammation.Upon reaching clinical effect Kremgen ointment should be taken once a day.Duration of therapy defines dermatologist individually.

reviews Kremgene: side effects

Prolonged use of the drug in some cases may cause such side effects like:

  • striae (stretch marks on the skin, skin atrophy strip);
  • fungal infections of the skin;
  • hirsutism;
  • hypertrichosis;
  • atrophy of the skin (due to the presence in the preparation of corticosteroids).

In addition, there may be allergic reactions and skin irritation at the site of application.Generally, side reactions occur due to the use of occlusive dressings.

Contraindications and overdose ointment Kremgen

Kremgen prohibited from using in such diseases as the patients:

  • lupus;
  • fungal and viral skin lesions;
  • syphilitic lesion of the skin;
  • skin tumors;
  • chickenpox;
  • primary purulent lesions of the mucous nasal and oral cavity, soft tissue, skin and eyes.

In addition, guests Kremgen not use under the age of two years, and if you are hypersensitive to the drug against hypersensitivity to its components.

Kremgena As for the use during pregnancy and lactation, the expert, if appointed these categories of patients must carefully evaluate the potential risk to the child and the expected therapeutic effect for the mother.


According to reviews of Kremgene experts, significant interactions of the drug with other drugs have been identified.

With regard to overdose in the event of prolonged use Kremgena in high doses to large areas of skin there is a probability of occurrence of such reactions on the part of the body as an increase in blood glucose levels and high blood pressure that require drug withdrawal.

According to Kremgenu instructions, the drug in pediatric patients should be used in children under the age of 2 years.

If you have allergies, fungal skin lesions or local irritation during treatment Kremgenom it advisable to cancel.

Kremgen Ointment should be stored in a dry, dark place at a temperature not exceeding 25 degrees Celsius.


Product description posted on this page is a supplement and a simplified version of the official version of the annotations to the drug.The information is provided for informational purposes only and is not a guide to self-medication.Before using the product you should consult with a specialist and to get acquainted with the instructions approved by the manufacturer.

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