1. active substance
2. Product form
6. dosage and Administration
7. Side effects
9. Conditions and terms
Casodex - a non-steroidal anti-androgenic drug with antitumor activity.
Casodex is available in tablet form.Medications sold in blister packs (Table 14. Each) are placed in cardboard boxes for two pieces.
50 mg to 150 mg
Excipients: magnesium stearate, lactose monohydrate, povidone, sodium carboxymethyl starch, purified water.
shell composition: titanium dioxide (E171), macrogol 300, hypromellose.
Indications Indications for Casodex purpose are the following diseases:
Contraindications Contraindications to receiving the drug are:
Casodex is used with extreme caution in patients with functional hepatic impairment, lack of lactase, with individual intolerance of lactose and galactose malabsorption syndrome / glucose.
take Casodex shown in adults and elderly men for a long time (at least for 2 years).The recommended dosing regimen - 150 mg 1 time per day.When the disease progresses the symptoms of the drug should be discontinued.
patients with functional disorders of the kidneys and liver dose adjustment is required.
In patients with severe to moderately severe functional hepatic impairment may experience an increased accumulation of the drug.
use of the drug can cause the following side effects:
Given the possibility of slowing down the accumulation and excretion of bicalutamide in patients with functional hepatic impairment, it is advisable from time to time to assess the functioning of the liver.Most of the changes of the body occur in the first 6 months of Casodex therapy.
Patients with disease progression on higher level prostataspetsificheskogom antigen need to consider discontinuation of Casodex.
Patients with lactose intolerance should be informed that the composition of each tablet contains lactose monohydrate (50 mg - 61 mg 150 mg - 183 mg).
Given the existing risk of inhibiting the activity of Casodex cytochrome P450 (CYP3A4), you must exercise caution when coadministered with drugs Casodex mainly metabolized with the participation of CYP3A4.
the appointment Casodex patients receiving coumarin anticoagulants requires regular follow-up of the prothrombin time.
Bicalutamide is contraindicated in pregnant and nursing mothers.
Casodex does not affect the ability of patients to control vehicles or engage in other potentially hazardous activities requiring psychomotor speed of reaction and concentration.
Store in a cool, dry place at a temperature not exceeding 30 ° C.Keep away from children.Shelf life - 4 years.
Product description posted on this page is a supplement and a simplified version of the official version of the annotations to the drug.The information is provided for informational purposes only and is not a guide to self-medication.Before using the product you should consult with a specialist and to get acquainted with the instructions approved by the manufacturer.
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