Influvac - instruction , application reviews


1. active substance

2. Product form

3. Composition

4. Indications

5. Contraindications

6. dosage and Administration

7. Side effects

8. Cautions

9. Terms and Conditions of storage

influvac - inactivated influenza vaccine.

active substance

influenza vaccines (inactivated) (Vaccine influenza virus inactivated).

release form

influvac comes in the form of suspension for subcutaneous and intramuscular injection.The preparation is realized in disposable syringes complete with needle injection (0.5 ml), in a carton box 1 or 10 sets.


suspension for subcutaneous and intramuscular injection

1 dose (0.5 ml)

One dose of vaccine contains neuraminidase (NA) and haemagglutinin (HA) of the followingviral strains:


A (H1N1)

A (H3N2)

15 micrograms HA

15 micrograms HA

15 micrograms HA

Excipients:sodium phosphate dihydrate, potassium dihydrogen phosphate, potassium chloride, sodium chloride, magnesium chl

oride hexahydrate, calcium chloride dihydrate, water for injection.


influvac appointed for the purpose of prevention of influenza in children from 6 months and adults.

Vaccination is recommended for all individuals and, above all, the categories of people who are at increased risk of influenza combination with existing pathological conditions:

  • patients with respiratory diseases.
  • Persons older than 65 years (regardless of their state of health).
  • patients with immunodeficiency diseases (malignant blood disease, HIV infection, and others.) And in patients receiving radiation therapy, cytotoxic agents, immunosuppressants or high doses of corticosteroids.
  • Patients with diseases of the cardiovascular system of any etiology.
  • patients with diabetes mellitus.
  • Patients with chronic renal failure.
  • Pregnant women (II-III trimester).
  • Children and adolescents (aged 6 months to 18 years), the host for a long time drugs containing acetylsalicylic acid, and as a result, at high risk of occurrence of Reye's syndrome due to influenza infection.

Contraindications Contraindications to receiving the drug are:

  • Severe allergic reaction temperature or after previous vaccination subunit influenza vaccines.
  • Individual hypersensitivity to chicken protein or other vaccine ingredients.
  • vaccination is postponed until the end of the exacerbation of chronic diseases and acute manifestations of the disease.In acute intestinal diseases of mild SARS and other diseases vaccination is performed immediately after the normalization of temperature.

Dosage and Administration

drug is intended for subcutaneous and intramuscular injection.

The immunization is carried out in the autumn period (annually).

Adolescents 14 years and older and adults the recommended dose is 0.5 ml dose.

Children aged 3 to 14 years is recommended to take once with 0.5 ml of the drug.

Children aged 6 months to 3 years are designated single 0.25 ml of the drug.

Children who have not previously been vaccinated and have not had the flu, as well as patients with immunodeficiency is necessary to introduce the drug twice with an interval of 4 weeks.

Rules vaccine administration

Before using the vaccine is necessary that it has warmed to room temperature.Immediately should shake the syringe prior to injection.Then remove the needle protection cap and remove air from the syringe, hold it upright up the needle and slowly pushing the plunger.During dose of 0.25 ml at a time when the inner surface of the syringe piston reaches the lower edge of the needle retainer its movement to be stopped.

The injection should be performed with caution in order to prevent ingress of the drug in the intravascular direction.

Intravenously administered influvac strictly prohibited.

Side effects

use of the drug may cause the following side effects:

  • central and peripheral nervous system : often - headache;rarely - Guillain-Barre syndrome, seizures, paresthesia, neuralgia, neuritis, encephalomyelitis.However, compelling evidence of the relationship of vaccination with these reactions have not been established.
  • Cardiovascular system: very rarely - vasculitis, accompanied by a transient functional renal impairment.
  • Musculoskeletal System: often - arthralgia, myalgia.
  • immune system: seldom - a manifestation of allergic reaction, very rarely - anaphylactic shock, angioedema.
  • blood and lymphatic system: rarely - transient lymphadenopathy, transient thrombocytopenia.
  • General disorders : often - fatigue, do not require treatment and passes after 1-2 days.
  • Systemic reactions : malaise, fever, chills, shivering, pain in joints and muscles.
  • Local reactions : ecchymosis, pain, swelling, redness, induration.
  • Dermatological reactions : often - increased sweating, generalized skin reactions including urticaria, pruritus, or non-specific rash.

Symptoms of overdose: currently insufficient clinical data on the risk of overdose is available.


The room in which the vaccination, you should have all the medicines for the emergency treatment of anaphylactic shock (including epinephrine / steroids / adrenaline and others.).

Patients with exogenous or endogenous immunosuppression may be insufficient immune response.

After vaccination, there is a risk of false-positive results based on the ELISA method (enzyme immunoassay) serological tests, in determining virus T-cell lymphotropic virus human (HTLV1), hepatitis C, antibodies against HIV1 (HIV).Exclude false-positive test results allows laboratory diagnosis by Western blotting.Transient false-positive results in some cases may be caused by the generation of IgM after vaccination.

Since influvac composition can include an undefined residual amount of gentamicin during vaccination of persons with hypersensitivity to aminoglycosides must be careful.

The composition 1 vaccine dose should not include more than 1 microgram of ovalbumin.

drug maintains its properties for 12 months.expiration date - 30 June of the year following the year of production.To use the vaccine after the expiration date printed on the packaging, should not be.

The drug has no effect on the ability to operate machinery and machinery or driving.

Conditions and terms

stored and transported out of the reach of direct sunlight, at a temperature between 2 and 8 ° C.The drug can be transported at a temperature of 25 ° C, but no longer than 24 hours.Keep away from children.Do not freeze.Shelf life - 1 year.


Product description posted on this page is a supplement and a simplified version of the official version of the annotations to the drug.The information is provided for informational purposes only and is not a guide to self-medication.Before using the product you should consult with a specialist and to get acquainted with the instructions approved by the manufacturer.

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