1. Pharmacological action
2. Indications Gliformina
3. Dosage and Administration
4. Contraindications to receive Gliformina
5. Side effects
6. Cautions while taking Gliformina
This drug enters the biguanide group (drugs used in diabetes) and has a hypoglycemic effect.
Available Gliformin 1000, 500, 250 mg tablets for oral administration.
According to the instructions, Gliformin is an anti-diabetic drug, taking it significantly reduces blood sugar levels.Currently, the mechanism of its effect on the body is not completely understood.
The main activities include Gliformina:
- suppression process of gluconeogenesis (formation of glucose molecules in the liver);
- activation of glycolysis (the breakdown of carbohydrates, particularly glucose);
- reducing the amount of glucose absorbed from the intestine.
According to reviews, Gliformin significantly improves insulin binding to receptors.
Acceptance of this drug for patients with d
addition to Gliformina manual says that the drug is able to provide fibrinolytic action, that is, its reception helps dissolve blood clots and prevent adhesion (sticking) of platelets.
glucose lowering while taking this drug is observed only in patients with diabetes, in healthy people Gliformin does not have such an impact.
Gliformin 1000, 500, 250 is indicated for insulin-dependent diabetes mellitus, particularly in cases where the disease is accompanied by obesity.A special condition in this case is the lack of inclination to ketoacidosis (violation of carbohydrate metabolism caused by insulin deficiency).
In some cases, the drug is used in combination with insulin:
- when resistance to the action of insulin diabetes (insulin resistance);
- at a diabetes-resistant treatment of sulfonylurea derivatives.
According to the instructions, Gliformin 1000, 500, 250 is administered orally after meals.
1. Scheme for patients not receiving insulin
In the first 3 days the drug is taken one tablet (Gliformin 1000) twice a day or one tablet (Gliformin 500) three times a day.Next, from the 4th to the 14th day of being received one tablet Gliformin 1000 three times a day.Then it is necessary to conduct blood and urine tests, in case the level of glucose in their significantly reduced, the dosage should be reduced.
2. Driving while taking Gliformina and insulin
In the case of insulin dose less than 40 IU / day, the dosage of the drug is identical to that described above.It is recommended to gradually reduce the dose of insulin to 4-8 IU / day, this process requires great care, which is why it is recommended in the hospital.In
Gliformina instruction specifies that during its maintenance therapy dose should not exceed 2.1 grams per day, i.e. 1000 2.1 mg tablets.
Gliformina The instructions stated that its reception should not be administered in the following cases:
- diabetic coma (complete loss of consciousness, which is characterized by the lack of reaction to external stimuli);
- in ketoacidosis;
- with lactic acidosis (excessive accumulation of lactic acid in the body);
- expressed in violation of the normal functioning of the liver / kidney and chronic diseases of the data;
- when lung / heart failure;
- myocardial infarction;
- during pregnancy and during breastfeeding.
Also notes that the receiving Gliformina 1000, 500, 250 is not recommended in the presence of infectious diseases, before major surgery and in the presence of injuries.
According to reviews of Gliformine, during his reception in the mouth may appear metallic taste.
In addition, in some cases on the skin rash of allergic nature.
the part of the gastrointestinal tract intake of this drug can lead to a violation of stool (diarrhea) and vomiting.
With the development of lactic acidosis should immediately stop taking the drug.
Gliformina Long-term use can lead to malabsorption in the gastrointestinal tract of vitamin B.
While receiving this drug requires constant monitoring of kidney function, in addition, it is recommended every six months to check the level of lactate in plasmablood.
When the danger of dehydration (dehydration) are not recommended to receive Gliformina.
In the event that the drug is taken in combination with sulfonylureas, must constantly monitor the level of glucose in the blood.
worth noting that reviews of Gliformine from professionals often positive.
Product description posted on this page is a supplement and a simplified version of the official version of the annotations to the drug.The information is provided for informational purposes only and is not a guide to self-medication.Before using the product you should consult with a specialist and to get acquainted with the instructions approved by the manufacturer.
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