Valium - instruction , application reviews


1. Indications Valium

2. Guide to Valium: side effects

3. Contraindications

4. Overdose

5. storage conditions

Valium is a drug, which is due to its active ingredient - alpha-lipoic acid (thioctic acid), regulates metabolism in the human body.

Patients with diabetes improves Valium in a blood plasma level of organic keto acids (pyruvic).

Berlition drug helps to prevent deposition of glucose in the blood vessels, endoneural stimulates blood flow, and improves the formation of the antioxidant component such as glutathione.As a result of the actions of the drug improves the function of peripheral nerves in patients with diabetic sensory polyneuropathy.In addition, alpha-lipoic acid facilitates the liver.

After oral administration the active ingredient of the drug is well absorbed in the gastrointestinal tract.When taken orally, Valium absolute bioavailability is 20% and the maximum plasma concentration observed after 30 minutes.The drug is mainly excreted by the kid

neys as metabolites, and its small part goes unchanged.As for the half-life, it is approximately 25 minutes.

According to the instructions to Valium it is produced in the form of solution for injection, in the form of gelatin capsules, as well as in the form of tablets - and Valium Valium 300 600.

Indications Valium

drug Valium is used mainly for the treatment of patients with alcoholand diabetic polyneuropathy, accompanied by paresthesias.In addition, this agent may be administered to patients who suffer from various liver diseases.

Capsules and tablets intended for oral administration.Do not chew or crush them.The daily dose is assigned to receive 1 (preferably half an hour before breakfast).According to the instructions of the Valium, to achieve the desired therapeutic effect is necessary to comply with its reception scheme.The medicine, usually take a long time, and the course of therapy determined by the attending physician.

In diabetic polyneuropathy adult patients are generally administered Berlition 600 (Valium two capsules one capsule 300 or 600 Valium) in 24 hours.When liver disease experts recommended the appointment Valium 600 once or twice a day depending on the severity of the disease.In the case of serious illness therapy should be started with the use of Valium in the form of a solution for infusion.

patients with diabetic polyneuropathy administered 300 to 600 mg per day (1 or 2 or ampoules Valium 300 600 1 ampoule Valium).For serious liver disease the recommended dose is 600-120 mg of thioctic acid a day (1 or 2 ampoules Valium 600).

Usually Berlition parenteral therapy in the form of carried over 2-4 weeks, then the patient is transferred to oral administration of Valium.

When administered parenterally drugs there is a risk of anaphylactic shock.Therefore, the appearance of weakness and nausea, as well as in case of itching urgent need to stop the introduction of drugs.Given some of the risks for the patient during therapy Valium, during infusion the patient should be under close medical supervision.

Persons with diabetic polyneuropathy is necessary to maintain optimal blood sugar levels and adjust the dosage of hypoglycemic agents, if necessary.

Guide to Valium: side effects

Application Valium can cause a variety of adverse reactions, among which are:

  • from the gastrointestinal tract: diarrhea disorders, nausea, vomiting, change in taste, violations of the chair;
  • with the CCC: tachycardia (rapid after intravenous administration), flushing of the face and upper body, pain and tightness in the chest;
  • CNS: a feeling of heaviness in the head, diplopia, convulsions (after a rapid intravenous administration);
  • allergic reactions: itching, skin rash, urticaria, eczema.In rare cases, anaphylactic shock may occur.

may also occur symptoms of hypoglycemia, headache, increased sweating, dizziness, and blurred vision.Sometimes there are shortness of breath, purpura and thrombocytopenia.At the beginning of treatment in patients with polyneuropathy could increase paresthesia with the feeling of pins and needles in the body.


Berlition Regulations states that the drug should not be used:

  • patients with individual hypersensitivity to the active substance preparation (alpha lipoic acid) and its other components.
  • persons under 18 years of age;
  • pregnant women;
  • lactation.

Tablets Valium 300 inhabited the Aural not prescribed to patients with galactosemia, lactase deficiency, as well as patients who have a violation of the absorption of glucose-galactose.Capsules Valium should not be used in patients with fructose intolerance.Application Valium patients suffering from diabetes requires close medical supervision (regular control of blood glucose).

Interaction with other drugs:

  • in the treatment of this tool is prohibited the use of ethyl alcohol;
  • when combined with tsisplastinom alpha-lipoic acid reduces its effectiveness;
  • drug enhances the action of hypoglycemic agents;
  • reception means containing calcium, magnesium and iron, as well as consumption of dairy products recommended no sooner than after 6-8 hours after administration of Valium, since it is capable of forming complexes with these elements.

Overdose If overdose of Valium can occur such symptoms as headache, nausea and vomiting, while increasing the dosage forms agitation and confusion.

Receiving more than 10 grams of the drug can cause the development of severe intoxication, even fatal.When combined with ethanol increased the degree of severity of poisoning several times and may be accompanied by:

  • occurrence of generalized seizures, and lactic acidosis;
  • decrease in blood glucose levels;
  • decrease in bone marrow function;
  • disseminated intravascular coagulation;
  • multiple organ failure and shock.

As pointed instruction to Valium, in the event of an overdose of a specific antidote exists.When receiving very high doses of the drug the patient should be hospitalized and to conduct intensive and symptomatic therapy.

According to reviews of the preparation, effectiveness of hemodialysis and hemofiltration during intoxication alpha-lipoic acid is not fully understood.

Storage conditions

Tablets are suitable for 2 years when properly stored (in a dry place at a temperature of 15-25 ° C).

capsules should be stored in a dry, dark place at a temperature not exceeding 30 ° C.Capsules Valium 300 are suitable for 3 years, and the shelf life of Valium 600 capsules is 2.5 years.


Product description posted on this page is a supplement and a simplified version of the official version of the annotations to the drug.The information is provided for informational purposes only and is not a guide to self-medication.Before using the product you should consult with a specialist and to get acquainted with the instructions approved by the manufacturer.

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