3. Treatment of toxic erythema
Distinguish acquired and congenital causes of skin diseases.Therefore, skin diseases can be of endogenous origin, i.e. caused by various changes in the internal environment and an exogenous origin, that is triggered by the environment.
About 20-50% of infants exposed to erythema.Typically, the disease develops in 2-4 day life.Etiology and pathogenesis of toxic erythema newborn have not been studied until the end.It was previously believed that the disease is a state border between normality and pathology.Recently found the formation of delayed-type hypersensitivity reaction that occurs on a background of toxic erythema newborn.The survey, conducted by RM Bakhtiarov and Shamova AG in 1982, was established a number of factors that have a direct influence on the formation of allergic reactions.Among them are the professional harm the mother (20%), family history (50%), toxicosis pregnant women (10%), taking
Among other risk factors for neonatal toxic erythemas, besides those mentioned above, can be isolated endocrinopathies such as diabetes, obesity, ovarian hypofunction, and thyroid dysfunction.Repeated pregnancy, intrauterine infection, fetal hypoxia, as well as the late start of breastfeeding may also affect the development of the disease in the newborn.
There is a basic division of neonatal toxic erythema, depending mainly on the nature of general and local clinical manifestations.Known limitations (unexpressed) and generalized form of the disease (severe).Limited form of toxic erythema characterized by normal general condition of the child, the emergence of a small number of eritematopapuleznyh elements, which are formed usually on the extensor surfaces of the extremities, back and buttocks.Eosinophilia in the blood is moderate (up to 5%).Generalized form toxic erythema newborn baby is characterized by impaired general condition, fever, lethargy and anxiety symptoms, as well as multiple eruptions papuleznourtikarnyh elements, which tend to merge, forming pustules and vesicles.In this case, eosinophilia in the blood is 12% or more.Most susceptible to generalized form of the disease boys.Rash disappeared, usually after 2-4 days of expression.In some cases, the manifestation of the new elements can be maintained until the end of the second week of life.Newborns who have had the disease, in particular, its generalized form, are at risk of further respiratory and allergic diseases.
toxic treatment of erythema in the first place is to eliminate allergens from the diet of the mother.In the treatment of neonatal toxic erythema, usually prescribe antihistamines and biological products, calcium gluconate, B6 vitamins, E, C, and Ruthin.Treatment of toxic erythema is also based on the creation of estrogen gipogormonalnogo background, which necessarily should be done early klemmirovanie cord.In the treatment of toxic erythemas be lubricated and vesicular pustular elements 2-3 times daily 1% brilliant green alcohol solution or 5% solution of potassium permanganate followed by powdering.
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