Molar pregnancy - Causes, Symptoms , Treatments


1. mechanism of development and causes cystic skidding

2. Types disease

3. Symptoms of cystic skidding

4. Diagnosis and treatment of diseases

Hydatidiform mole - a disease of the ovum in a pregnant woman, in which the epithelial layer expands villous membrane, and of chorionic villi (future placenta) form bubbles in the liquid.

Hydatidiform mole is quite rare pregnancy abnormalities.It occurs in 0,03-0,8% of pregnant women.

mechanism of development and causes cystic skidding

The disease belongs to the pathology of the trophoblast.Trophoblast called interim authority, which is required for the connection of child embryo to the uterine wall.In the future, it is formed from the placenta.Trophoblast is the tissue that formed in the early stages of embryo development.After appears placenta, trophoblastic formed from extraembryonic tissue.This fetal tissue forms part of the septum that separates the mother's body and fetus embryo and provides nutrition.

In the case of cystic degeneration of the trophoblast skid occurs in a large number of small bubbles.Occupying the entire uterine cavity, they quickly grow and spread.Hydatidiform mole cells produced human chorionic gonadotropin (hormone of pregnancy).Normally, the hormone produced during pregnancy, but in much smaller numbers.The embryo at this disease die in early pregnancy.

most common molar pregnancy occurs in women during the second and subsequent pregnancies.In addition, this disease occurs in early to mature teenagers.About 45% of the disease are women between the ages of 40 to 45 years.

Experts suggest the following reasons for hydatidiform mole.

1.Gormonalnye disorders in pregnant women.Most often, the disease provokes insufficient production of the hormone estrogen.

2.Dostatochno common cause of hydatidiform mole - infectious and viral diseases.By pathological changes usually cause toxoplasmosis (a parasitic disease caused by protozoa).

3. Genetic abnormalities.Chromosomal abnormalities in pregnant women can lead to the development of the pathology of the ovum.

addition to the above reasons hydatidiform mole, there are some risk factors for this disease.The risk group includes pregnant women older than 35 years.In addition, such factors include spontaneous abortion.Moreover, each subsequent spontaneous abortion increases the risk of disease in several times.

When this pathology occurs repeatedly, a woman develops infertility.

Types disease

Experts distinguish between three types of the disease.

simple or full.For this kind of hydatidiform mole characterized by pathological changes in the whole chorion.A simple form of the disease occurs in the first trimester of pregnancy.Fruit woman dies and dissolves over time.

Partial.It is characterized by pathological changes of only a portion of the chorion.Partial view of developing the disease after the first trimester of pregnancy.It is often the pregnancy continues to grow and as a result the child is born alive.In case of partial molar pregnancy usually occur premature birth.

destruirujushchego.The most severe form of malignant disease.

In the case of pathology in multiple pregnancies may be affected by only one or two placentas.

Symptoms of cystic skidding

clinical picture of the disease is quite diverse.In the initial stages of cystic skidding no symptoms, a pregnant woman feels well.However, with such a disease in women often develops toxicosis, nausea, vomiting, edema.Furthermore, in gynecological examination showed a significant increase in the uterus.So when in the period of three months corresponds to the size of the uterus is a five-month pregnancy.

main symptom of hydatidiform mole are bloody vaginal discharge after menstruation delay for a long time.Some pregnant women with this pathology are uterine bleeding.Usually they occur in the first trimester of pregnancy and continuing until delivery or removal of pathology.Discharge or bleeding dark red color may be different intensity.

In cases where molar pregnancy provokes a miscarriage, bleeding join a strong cramping in the lower abdomen.

Persistent bleeding can cause iron deficiency anemia pregnant women.

The signs of this disease also include increased blood pressure, headaches, bloating.If germination uterine wall having intense pain in the abdomen.

In rare cases it is possible metastasis cystic drift to other organs of women.When lung metastases in women there is a cough, often with hemoptysis.Metastases in the brain causes headaches, high-intensity, and other neurological symptoms.

Diagnosis and treatment of diseases

diagnosis of cystic skid includes a pelvic examination, medical history, laboratory and instrumental investigations.

Laboratory tests are to conduct a blood test, biochemical determination of the level of creatine, of coagulation.It is mandatory to study the content of the hormone human chorionic gonadotropin.

most informative method of research is ultrasound of the uterus.In addition, for the registration of fetal heart tones spend phonocardiography.

If necessary, appoint a woman laparoscopic sonography (ultrasound diagnostics), hysteroscopy (examination of the inside of the uterus), UZGSS (study of tubal patency).

Treatment of hydatidiform mole is usually done surgically.But in some cases, it may be spontaneous release.To this end, during the bleeding thick wads introduced into the vaginal cavity.Then spend an injection medicines that increase the motility of the uterus.If such therapy fails, surgical treatment of hydatidiform mole.

most commonly in the treatment of this disease apply vacuum aspiration.After the procedure, to better uterine patients received intravenous oxytocin.

In some cases, the treatment of cystic skidding use removal of the uterus.It is used for large scale or significant uterine bleeding, when vacuum aspiration inefficient.In this woman's ovaries are not removed.

If after removing the bubble drift levels of the hormone human chorionic gonadotropin increases, carry out preventive chemotherapy.


This article is available exclusively in the educational purposes and is not research material or professional medical advice.

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