Lymphocytic leukemia - causes, symptoms, treatment, prognosis


1. Symptoms of acute lymphocytic leukemia

2. symptoms of the chronic form of the disease

3. Treatment of diseases

4. forecast lymphocytic leukemia

lymphocytic leukemia -disease characterized by malignant lesion formed in lymphatic tissue.It provides lymphoblastic tumor accumulation of lymphocytes in lymph nodes, bone marrow and peripheral blood.Previously, acute lymphocytic leukemia was considered primarily a children's disease, since it is children aged 2 to 4 years are more prone to this disease.To date suffer from the disease, usually adults.When

lymphoblastic lymphoid tissue grows in the lymph nodes, liver, bone marrow, spleen and some other organs.

Now lymphocytic leukemia occurs mostly among the elderly.It should also be noted that men are more prone to this disease than women.Not the least role in the predisposition to lymphatic leukemia heredity plays.

There are two main forms of lymphocytic leukemia: chronic lymphocytic leukemia (lymphocytic leukemia) and a

cute lymphocytic (lymphoblastic leukemia).

Symptoms of acute lymphocytic leukemia

During diagnosis studied peripheral blood, in which the doctor can detect the characteristic blasters.The study of blood smear established presence of mature cells and blasters, with no intermediate stages.

Among the main symptoms of lymphocytic leukemia in the acute form can be isolated normochromic anemia and thrombocytopenia.Among others, the rarer symptoms of lymphocytic leukemia, can be identified leukocytosis and leukopenia.

Accurate diagnosis can be made only after a special study that affects the bone marrow.

Among the main symptoms of lymphocytic leukemia in the acute form can be identified disappearance of appetite, malaise and weakness, weight loss, shortness of breath and a dry cough.Anemia, unmotivated rise in temperature, nausea, headache, and abdominal pain are also symptoms of lymphocytic leukemia in the acute form.Among other lymphocytic leukemia symptoms can be isolated pain in the extremities and spine, a condition of intoxication, increased irritability, increased peripheral lymph nodes.Approximately half of these patients the development of such symptoms lymphocytic leukemia acute form as hemorrhagic syndrome (accompanied by bleeding and petechiae), infiltration of the testes (in some cases), and there is also a risk of formation of foci of extramedullary lesions in the central nervous system that may lead toneuroleukemia.

symptoms of the chronic form of the disease

Chronic lymphocytic leukemia - a cancer of the lymphatic tissue, accompanied by the accumulation of neoplastic lymphocytes in the peripheral blood.A characteristic feature of chronic lymphocytic leukemia is slow enough for it as compared with the acute form.In the later stages of the disease can be observed violations of blood.

Thus, among the main symptoms of chronic lymphocytic leukemia can be distinguished unwell (asthenia), general weakness, sudden weight loss, increased susceptibility against various types of infections, decreased appetite, and increased liver size (hepatomegaly).The feeling of heaviness in the abdomen, excessive sweating, swollen lymph nodes and spleen, anemia and thrombocytopenia (a symptom associated with decreased levels of platelets in the blood below a certain norm) are also symptoms of chronic lymphocytic leukemia.Among other symptoms of chronic lymphocytic leukemia in the form can be identified shortness of breath, provoked by heavy physical exertion, frequent allergic reactions, as well as netropeniyu (symptom, accompanied by a decrease in neutrophil granulocytes in the blood level).

Treatment of diseases

distinctive feature of the treatment of lymphocytic leukemia is the inappropriateness of his conduct in the early stages.This fact allows patients for a long time to go without drugs, and without complying with certain restrictions.

therapy is applied only in acute lymphocytic leukemia, and only in the case of pronounced manifestations of the disease.lymphocytic leukemia treatment is carried out if there is a rapid increase in the number of lymphocytes, as well as a sufficiently rapid increase in the spleen, lymph nodes progressive increase in the size and growth of thrombocytopenia and anemia.

lymphocytic leukemia treatment is performed whenever there are indications of tumor intoxication, among which are the rapid loss of weight, sweating at night, constant fever and general weakness.

To date, treatment of lymphocytic leukemia is based on chemotherapy.Previously, the procedures used extensively hlorbutin but purine analogues used today.Bioimmunoterapiya - lymphocytic leukemia treatment based on the use of monoclonal antibody type.Their administration facilitates the selective elimination of tumor cells, thereby avoiding damage to healthy tissue.

High-dose chemotherapy administered in the case, if the above methods of treating lymphocytic leukemia does not bring the desired effect.High-dose chemotherapy provides for subsequent transplantation of hematopoietic stem cells.Radiation therapy is used in the presence of a sufficiently large tumor mass.Radiation therapy is auxiliary in the treatment of lymphocytic leukemia.

In some cases, a strong increase of the spleen, the organ is completely removed.

diagnosis of this disease are involved, usually a hematologist and internist.

forecast lymphocytic leukemia

forecast lymphocytic leukemia in the chronic form today is conducted on a qualitative level.Thus, there are three main prognostic groups.

In the first group lymphocytic leukemia prognosis is the slow course of the disease, accompanied by an increase in the number of lymphocytes in the blood.For this group is characterized by the absence of symptoms and the need for treatment.

Next forecast lymphocytic leukemia is characterized by a steady progression that occurs in patients who are at standard risk.During this period, there is a need in the treatment of disease.

in high risk forecast lymphocytic leukemia is characterized by fairly active passage and development.Treatment should begin immediately after diagnosis.


This article is available exclusively in the educational purposes and is not research material or professional medical advice.

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