Gliosis of the brain - causes, symptoms, lesions , treatment


1. foci of gliosis

2. Gliosis brain

3. Treatment

Gliosis - a condition characterized by the replacement of lost or deformed due to the various types of tissue damagecentral nervous system glial cells (glia).

Depending on the nature and location of proliferation of glial cells are several types of gliosis:

  • Anizomorfny view - is characterized by chaotic arrangement of proliferating glial fibers.
  • fiber type - form of gliosis in which glial fibers are more pronounced than glial cell elements.
  • Diffuse view - amazing enough large tracts of the spinal cord and brain.
  • Isomorphic type - characterized by a relatively regular arrangement of proliferating glial fibers.
  • Marginal view - accompanied by a proliferation of glial fibers podobolochechnyh mainly in areas of the brain.
  • Perivascular view - gliosis form in which the fibers are surrounded by sclerotic inflamed blood vessels.
  • subependymal form - characterized by an arrangement of glial fibers in the brain areas under epen

replacement of lost tissue mechanism develops, usually due to nerve tissue damage to their structural units, i.e. neurons, glia sprawling replacing their cells.Thus, cell lesions data block, thereby protecting intact tissues.

The central nervous system consists of neurons, glia and ependyma (gly).Neurons - the main cells that provide education and pulse transmission.Ependyma - cells located in the central canal of the spinal cord, and the cerebral ventricles.Neuroglia - auxiliary nerve tissue cells, which constitute about 40-50% of the volume of the central nervous system.The main function of glia is to protect and restore nerve tissue after previous infections and injuries.Moreover, these cells provide a working metabolic processes in the central nervous system.

As a result, proliferation of glial cells on the site of the lesions formed gliosis.The value gliosis is a specific value that is calculated from the ratio of enlarged glial cells to other cells in the central nervous system per unit volume.

foci of gliosis

foci of gliosis are abnormal growths accumulations of glial cells that replace damaged or destroyed neurons.Outbreaks gliosis formed as a result of pathological processes and diseases, among which are the tubercular sclerosis, multiple sclerosis, epilepsy, hypoxia, birth injuries, chronic hypertensive encephalopathy, prolonged hypertension and inflammation (encephalitis of different origin).

In order to identify foci of gliosis performed magnetic resonance imaging, the results of which determined the dislocation of foci of gliosis, their size, and in some cases, information on the duration of the disease.Through magnetic resonance imaging in conjunction with other types of research neurologist can determine the cause of the formation of gliosis focus, as well as to determine the consequence of active or adjourned CNS process is the focus.

In most cases, gliosis is not expressed, so its presence is often installed in the survey, conducted on an entirely different reasons.It should be noted that if there should not be treated gliosis hearth, and the disease, in which it was formed.

Gliosis brain

Gliosis brain - a form of the disease, which develops as a result of hereditary diseases of lipid metabolism and lead to the defeat of the central nervous system.

Gliosis brain - a phenomenon quite rare.Gliosis of the brain is caused by a gene mutation that provides synthesis of hexosaminidase A, which is an enzyme directly involved in the metabolism of gangliosides.Gangliosides, accumulating in the cells of the central nervous system, disrupt their functioning.As a result of an autosomal recessive mode of inheritance there is a chance of conception if both parents are carriers of the mutant gene.

In the first months of life with gliosis newborn brain develops absolutely normal.Recourse to the physical and mental development of the child is celebrated for 4-6 month.At the same time, as a rule, lost eyesight, hearing, ability to swallow, having convulsions, muscle atrophy occurs and paralysis.The maximum duration of life of newborns with brain gliosis is 2-4 years.


Treatment gliosis can not be, because it is not an independent disease, but a symptom of various types of pathological processes.To avoid the formation of new lesions treat the cause of the disease.

However, the prevention and treatment of gliosis in the formation of foci is primarily in the rejection of fatty foods in large quantities, since it has a detrimental effect on the brain.The fact that a large amount of fat, regularly entering the body, damage or destroy neurons controlling body weight.Within a few months fat saturation neurons are significantly reduced in number, while the foci of gliosis grow while replacing damaged neurons.

specific treatment gliosis in hereditary disease of fat metabolism does not exist.However, at 18-20 weeks of pregnancy as a result of the analysis of the amniotic fluid it is possible to establish a diagnosis.In the case of the fetus corresponding diagnosis of pregnancy termination is recommended.

gliosis Prevention and treatment are based on leading a healthy lifestyle and regular surveys among experts.There is no effective treatment gliosis, however, prevent or suspend its development is quite real.


This article is available exclusively in the educational purposes and is not research material or professional medical advice.

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