Hyperuricemia - Causes, Symptoms , Diet , Treatment


1. Causes of hyperuricemia

2. diagnosis and clinical manifestations

3. treatment of hyperuricemia

is a growing number of cases of children with each Yearand adult diseases such as hyperuricemia.According to research data skrinningovyh given pathological condition associated with disorders of purine metabolism, it is observed in almost 20% of adults and 3% of the child population of the globe.The increase in metabolic disorders of purine warping have been linked to adverse environmental conditions in the world, in particular with an increase in toxic emissions of combustion products of gasoline engines, which are extremely negative impact on the purine metabolism.

What is this disease, what are the symptoms and causes of hyperuricemia?Historically, that this pathology is more known for its clinical manifestations, ie, nephrolithiasis, and gout.In fact, hyperuricemia - a high blood uric acid human.Until recently, this disease does not attract much attention, because it has a

low prevalence in the population, but recent research into the impact of this disease on the course of heart disease, forced experts to look at the disease through different eyes.The main symptoms of hyperuricemia - is to increase the level of uric acid in the blood chemistry.If the disease progresses, according to the symptoms of hyperuricemia join the clinical manifestations of gout.

should also be noted that hyperuricemia in a pregnant woman is extremely dangerous for the fetus as it promotes the formation of congenital anatomical or histological nephropathy.Today there are three pathogenic species of hyperuricemia:

  • kidney;
  • metabolic;
  • mixed.

normal concentration of uric acid in the blood is in the range 240-400 m / l.Some experts rather critical of the high-threshold and is considered borderline level of uric acid in the amount of 354 m / l.

modern man, consumed with food in excess amount of sodium chloride, hyperuricemia may lead to the development of hypertension, and can significantly increase the risk of complications of various cardiovascular diseases.There are medical and nefarmokologicheskoe treatment of hyperuricemia, which is subject to a specific diet aimed at reducing levels of uric acid.

Causes of hyperuricemia

Causes of hyperuricemia of renal type are the three main factors:

  • participate in purine metabolism;
  • excessive formation of uric acid due to its high content of fructose in the diet;
  • violation excretion of uric acid due to impaired renal function.

Renal hyperuricemia may be either hereditary or acquired in nature.The trigger, regardless of the cause of hyperuricemia, is a violation of filtration and tubular kidney function.Renal hyperuricemia, which is acquired in nature, most often occurs in the elderly in the background sclerosis renal vessels due to atherosclerosis, diabetes, hypertension, or as a result of unjustified long-term use of certain medications, such as diuretics or aspirin.

Causes of hyperuricemia can be in blood diseases, which are accompanied by a massive collapse of the nucleotides in the cell nucleus - a variety of diseases of the lymphatic system, blood disease, sarcoidosis, psoriasis and other diseases, which could cause renal excretion.

main causes of hyperuricemia acquired character lie in the constant use of purine-rich, or high-calorie, fatty foods.It is also a very negative impact on the metabolic processes has an alcohol.Such foods cause the body an excess of uric acid synthesis substrate.In addition, fatty foods seriously affect the urate excretion by the kidneys.Therefore, in the treatment of diseases of particular importance in the diet of hyperuricemia.

diagnosis and clinical manifestations

Most often, hyperuricemia is not from the person no complaints and takes almost no symptoms, and the identification of metabolic, usually occurs in the case of a medical examination.The symptoms of hyperuricemia mostly nonspecific.In children, this pathology can appear constipation, nocturnal enuresis, abdominal pain, excessive sweating, tics and logoneurosis.In adolescents, there are hyperuricemia symptoms such as itching in the urethra, pain, overweight, biliary dyskinesia.Also, symptoms may start to signs of intoxication and asthenia.In patients with hyperuricemia frequently diagnose various diseases of digestive tract disorders and symptoms of the metabolic processes of the myocardium.

treatment of hyperuricemia

One of therapeutic areas in the treatment of hyperuricemia is diet therapy, which provides for reduction of consumption of those foods that contain purine bases.Significantly limited intake of strong tea and coffee, fatty fish, foods containing gelatin in the composition.From diet to exclude spirits and beer, hearty fish and meat soups, baked, fried, stewed meat and fish, smoked, canned, sausages.Diet for hyperuricemia intended to limit the consumption of chocolate, cocoa, spinach, sorrel, cauliflower.

Proper diet for hyperuricemia plays a paramount importance.The diet must enable those fruits and vegetables that contain a lot of potassium - eggplant, pumpkin, cabbage, peas, squash, apricots, peaches, bananas, melons, pears, grapes, cucumber, carrots, etc.

From berries most.useful in bright red, blue and black fruits - cherries, cherries, blueberries, cranberries, blackberries, cranberries, etc.They contain substances help lower uric acid levels.Also diet for hyperuricemia include drinking plenty of fluids.On the day you need to drink at least 2.5 liters of liquid that has the ability to dilute the urine, preventing the formation of kidney stones.

very useful to add a small amount of drinking water, cranberry juice, cranberries, or a lemon.In addition, it is necessary to carry out weekly fasting days.Following these simple guidelines will help to avoid the further development of diseases associated with high levels of uric acid in the blood.Such treatment of hyperuricemia is quite feasible for a person.

Drug treatment of hyperuricemia involves taking medications that increase the renal clearance of uric acid.Very effective drug in this field is Probenecid.Allopurinol, which helps to reduce purine production and increase excretion oksipurinov - inhibitor ksantinokidazy also widely used.Drug treatment of hyperuricemia and develop an individual plan of nutrition in people with the disease should be performed only by a specialist, because self will lead to severe complications of the pathology - the development of gout.


This article is available exclusively in the educational purposes and is not research material or professional medical advice.

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