1. composition and the form of
2. Pharmacological Effects of vitamin D3
3. Indications "Vitamin D3» solution
4. Contraindicationsuse this solution
5. Dosing of vitamin D3
6. Side effects
7. overdose of vitamin D3
8. storage conditions and shelf-life of vitamin D3
vitamin D3(international name - Kolekaltsiferol) is a vitamin substance shall be taken by both adults and infants.This drug makes up for a deficiency of vitamin D3.It participates in the regulation of calcium-phosphorus metabolism and increases the absorption of Ca2 + and phosphate in the gut.
issue in the present time Kolekaltsiferol released in the form of a clear, slightly yellowish solution for oral administration.
One milliliter of the above means contains in its composition of 200,000 IU kolekaltsiferola and medium chain triglycerides (up to 1 milliliter).Implement
the vitamin preparation into dark glass bottles at 20, 25, 30 and 50 milliliters, in cartons, as well as in glass vials with caps, droppers 15, 30 and 50 milliliters, in cardboard packs.
According to the instructions Kolekaltsiferol up for a deficiency of vitamin D3.It increases the absorption of calcium and phosphate in the gut, as well as their reabsorption in the renal tubules.Also, this vitamin is involved in the regulation of calcium-phosphorus metabolism, promotes normal functioning of the parathyroid glands, bone formation and mineralization of skeleton and teeth in children.
As for absorption, it is fast enough.vitamin penetrates from the small intestine into the lymphatic system, and then enters the liver, and then - into the general circulation.Drug accumulates in adipose tissue, adrenal gland, skeletal muscle, liver, bone, kidney and myocardium.Kolekaltsiferol crosses the placental barrier and is excreted in breast milk.Vitamin metabolized in the kidneys and liver.He deduced with bile and kidneys (min).
According to the instructions, vitamin D3 is indicated for the treatment and prevention of hypo-and vitamin D3, and hypoparathyroidism (idiopathic, post-operative, tetany, pseudohypoparathyreosis).In addition, Kolekaltsiferol used in states increased the body's need for vitamin D3:
Vitamin D3 (according to reviews of medical specialists) should not be used in conditions such as:
With extreme caution taking vitamin D3 solution in atherosclerosis, congestive heart failure, sarcoidosis, hyperphosphatemia, nefrourolitiaze (even in history), chronic renal failure, pregnancy, lactation and in children.
vitamin D3 for infants to prevent rickets, as a rule, appointed in the autumn and winter.Kolekaltsiferol best taken in the morning.Pediatricians active drug administered to infants, one or two drops (500-1000 IU) per day.Giving your child a vitamin needed during feeding or after a meal.The above means before use should be diluted with 10-15 ml of water.The duration of prophylactic ranges from thirty to forty-five days.
to treat rickets, hypocalcemia and spazmofilii Kolekaltsiferol prescribed by 200,000 IU once every seven days for two weeks.
To prevent tetany take vitamin D3 at 1,000,000 IU per day.
In osteoporosis and osteomalacia prescribe the drug for 200,000 IU every fifteen days for three months.
When pseudohypoparathyreosis and hypoparathyroidism prescribe this vitamin for 7500-15000 IU per day.
Infants suffering spazmofiliey appoint Kolekaltsiferol 5000 IU three times a day.
According to the instructions, vitamin D3 (customer feedback is also supported) can trigger the development of the following side effects:
Symptoms of acute intoxication kolekaltsiferola: diarrhea or constipation, thirst, headache, dryness of the oral mucosa layer, nocturia, pollakiuria, polyuria, nausea, vomiting, anorexia, weakness, unusual fatigue, hypercalciuria, hypercalcemia, blurredurine, bone pain, itching, hypertension, drowsiness, arrhythmias, photosensitivity of the eye, a change of mood and psyche, weight loss, gastralgia, pancreatitis, conjunctival hyperemia.
Clinical signs of chronic intoxication with vitamin D3: calcification of the lungs, kidney, soft tissue, blood vessels, cardiovascular and renal insufficiency, hypertension, impaired growth in children.
overdose Treatment includes the following events: the abolition of the vitamin, diet with minimal calcium content, the appointment of GCS, ascorbic acid, thiamin, retinol, alpha-tocopherol, the consumption of vast quantities of liquid.In severe cases resort to intravenous electrolytes, furosemide, 0.9% sodium chloride as well as hemodialysis.
Reviews pharmacists suggest that the drug should be stored out of the reach of children and protected from direct sunlight, at a temperature between 15 and 25 degrees Celsius.
kolekaltsiferola shelf life of five years from the date of issue.
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