Vitamin B5 - properties, application , deficiency symptoms


1. biological significance of vitamin B5

2. daily requirement for calcium pantothenate

3. Indications of vitamin B5

4. The use of vitamin B5 inampoules and tablets

5. Symptoms of deficiency of vitamin B5

6. content of vitamin B5 in foods

7. Interaction

vitamin B5 (pantothenic acid or calcium pantothenate) refers to water-soluble vitamins.It is found in cereal products and cereal beer yeast and some fruits.The role of pantothenic acid in the body is extensive.This vitamin is necessary for metabolism of carbohydrates, fats and amino acids, as well as hemoglobin synthesis, acetylcholine, histamine, cholesterol and fatty acids.

biological significance of vitamin B5

Vitamin B5 plays a key role in the process of energy production by the human body.It is present in the composition of coenzyme A - a substance involved in the metabolism of proteins, carbohydrates and fats.In addition, calcium pantothenate improves the body's response to external stimuli, promotes

wound healing, boosts immunity and intelligence.

Pantothenic acid takes an active part in the formation of antibodies.She also participates in the metabolism of fatty acids, stimulates the redox processes, normalizes lipid metabolism and helps the body absorb other vitamins.

Another important property of the calcium pantothenate is its ability to stimulate the production of glucocorticoids, vitamin B5 thereby actively used in capsules for the treatment of heart diseases, arthritis, colitis, and allergies.

In cosmetic practice pantothenic acid is used to maintain hair health, combating acne and wrinkles.

daily requirement for calcium pantothenate

exact daily human need for vitamin B5 is not installed.For adults it is about 10-12 mg and for children - up to 2 mg.Pregnant and breastfeeding women should receive daily at least 15-20 mg of pantothenic acid.The body's need for this vitamin is partially satisfied by its production of intestinal microflora.In an average day, it synthesizes 3,4 mg calcium pantothenate.

Indications of vitamin B5

vitamin B5 in tablets and ampoules is recommended in combination with other B vitamins with sleep disorders, excessive fatigue, loss of appetite, nausea and dermatitis.

In addition, indications for additional reception of pantothenic acid are the following diseases and factors:

  • asthma;
  • chronic and acute bronchitis;
  • neuralgia, polyneuritis;
  • circulatory failure;
  • eczema and trophic ulcers of the skin;
  • gipomotornaya intestine dyskinesia;
  • chronic disease (celiac disease and regional enteritis);
  • allergic reactions;
  • increased physical activity;
  • alcohol abuse;
  • age over 55 years;
  • pregnancy and lactation period;
  • long the patient being in a state of stress.

In addition, vitamin B5 tablets shown persons with an increased need for nutrients, as well as those who consume low-calorie or insufficient vitamin-rich food.

The surgery vitamin B5 in ampoules used to eliminate intestinal atony after surgical interventions in the gastrointestinal tract.

The use of vitamin B5 in ampoules and tablets

pantothenic acid administered orally, intravenously or intramuscularly.

Vitamin B5 tablets adults appoint 0.1-0.2 grams 2-4 times per day for children aged 1-3 years - 0.005-0.1 grams 2-4 times per day, children from 3 to14 years - 0.1-0.2 gram twice daily.The maximum daily dose for adults is 0.4-0.8 grams, and for children - 0.1-0.4 grams.

calcium pantothenate, are generally well tolerated by the body.At its ingestion may develop dyspeptic phenomena, while intramuscular injections - a slight pain upon administration of the drug.

Symptoms of deficiency of vitamin B5

Since pantothenic acid often occurs in food, its deficiency is very rare.Pantotena Lack of calcium in the body can cause an insufficient amount of vitamin B5 in foods that make up the daily human diet.Deficiency of the vitamin can develop in the presence of small intestinal malabsorption syndrome disease, and long-term use of antibiotics and sulphonamides.

Signs of deficiency of vitamin B5:

  • weakness and fatigue;
  • abdominal pain;
  • loss of appetite;
  • irritability, anxiety and depression;
  • palpitations;
  • eczema;
  • insomnia;
  • nausea and vomiting;
  • muscle spasms;
  • loss of coordination and burning pain in the legs;
  • hair loss;
  • frequent respiratory infections.

content of vitamin B5 in foods

Rich dietary sources of pantothenic acid include: pork kidney and liver, eggs, beef liver and kidney, soybeans, split peas, beans and fish (sardine, chum).

calcium pantothenate is also found in brewer's yeast, chicken meat, lobster, milk, cereal sprouts, whole grains, bran, lentils, avocados, broccoli, oranges and bananas.

vitamin B5 Activity in food is sharply reduced under the influence of ultraviolet irradiation, and heat preservation.


Pantothenic acid enhances the absorption of potassium and folic acid, as well as enhances the action of cardiac glycosides and drugs that improve intestinal motility.

Vitamin B5 reduces the toxic effects of streptomycin and other anti-TB drugs.

concentration of calcium pantothenate falling under the influence of barbiturates, alcohol, and caffeine.

Vitamin B5 actively excreted from the body diuretics.Reception of proteolytic enzymes that degrade protein, and leads to the destruction of pantothenic acid.

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