12 August

Vitamin B12 - properties and application sources

Contents:

1. Pharmacological properties

2. Application of vitamin B12

3. Dosing and Administration

4. Side effects and contraindications of vitamin B12

5. products with vitamin B12

vitamin B12 - a synthetic analogue of the natural vitamin B12: an essential component, which is involved in hematopoiesis, regulates fat and carbohydrate balance of the body and has a huge impact on the functioning of the nervous system.Lack of this vitamin leads to anemia (anemia), which threatens to diseases of the stomach and liver, chronic fatigue, stress, and many other serious diseases and disorders.

The main active ingredient of the drug is cyanocobalamin.Vitamin B12 is produced as a solution for injection.One vial contains vitamin B12 1 ml of a solution which includes a 200 or 500 mcg of cyanocobalamin.

Pharmacological properties

Cyanocobalamin has hematopoietic and metabolic effects.Once in the body it is converted into adenosyl cobalamin (kobamamid), which is necessary to restore and f

olic acid tetrahydrofolic.Kobamamid is an essential component that is necessary for the formation of creatine, DNA, deoxyribose, and many other substances, and enzymes responsible for normal functioning of all systems and organs.

Vitamin B12 is directly involved in the process of blood: it was he who contributes to the normal maturation of red blood cells and increases their tolerance to hemolysis.

As a result of the use of vitamin B12 activates the blood coagulation system and increases the body's ability to regenerate tissue.In addition, this drug has a beneficial effect on the function of the nervous system and liver, and also lowers the concentration of cholesterol in the blood.

Application of vitamin B12

Ampoules Vitamin B12 - is one of the drugs used in traditional medicine for the treatment of various hematological disorders.In particular, these include:

  • chronic anemia, accompanied by a deficiency of vitamin B12 (alimentary macrocytic anemia, Addison-Birmera disease);
  • iron deficiency anemia;
  • aplastic anemia;
  • hemorrhagic anemia;
  • anemia caused by exposure to toxic or potent drugs.

Furthermore, cyanocobalamin may be used in the treatment of liver failure, hepatitis, cirrhosis, alcoholism, neurological and dermatological diseases, gastrointestinal diseases, renal disorders and infectious processes occurring continuously.

Dosing and Administration

vitamin B12 injections may be performed by subcutaneous, intramuscular, intravenous, and in some cases - intralyumbalno.Driving dosage depends on the indication and patient population:

  • with aplastic anemia is administered 100 mcg of the drug during the period necessary for the occurrence of significant clinical and hematological improvement;
  • when post-hemorrhagic anemia and iron appoint 30-100 mg of the drug 2 or 3 times a week;
  • with nutritional anemia in premature infants or young children are introduced to 30 micrograms of vitamin B12 in 15 days.

Patients with anemia Addison-Birmera spend combination therapy, including injections of vitamin B12 and folic acid.

Side effects and contraindications of vitamin B12

Cyanocobalamin may be imposed only after an accurate diagnosis, revealing the deficiency of this vitamin in the body, as well as the absence of contraindications.The main contraindications to the use of vitamin B12 as follows:

  • hypersensitivity;
  • erythremia;
  • thromboembolism;
  • polycythemia;
  • during pregnancy and lactation.

In addition, the drug is prescribed with caution in the presence of benign or malignant tumors, accompanied by a deficiency of vitamin B12, and a tendency to thrombosis and megaloblastic anemia.Patients with angina means should also be appointed in limited doses.

Side effects resulting from the treatment of cyanocobalamin may manifest as dizziness, headache, mental excitation, diarrhea, tachycardia, and allergic reactions cardialgia.In the application of high doses of the drug can also be observed hypercoagulability and disruption of purine metabolism.

products with vitamin B12

products with vitamin B12 should be included in the diet on a regular basis and in sufficient amounts, as they help to maintain normal hematopoietic function of the body and is an excellent prevention of various diseases of the liver, nervous system, skin, and other organs andsystems.

is especially important to eat enough food rich in this valuable vitamin persons who are engaged in sports or constantly practicing strong physical exertion, as well as women during pregnancy and breastfeeding.

believed that most antianemic vitamin include the following food: veal liver, salmon, sardines, beef, lamb, shrimp, cod and cod liver oil, milk and yogurt.

Among the most useful products included in the vegetarian diet, we can distinguish soybeans, lettuce, spinach, green onions, wheat germ and sea kale.

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