Properties and application of vitamin B1, vitamin source


1. Medicinal properties

2. daily requirement

3. vitamin B1 deficiency in the body

4. Sources of vitamin B1

5. The use of vitamin B1 in ampoules

6. Contraindications to the use of vitamin B1

7. interaction with other drugs

vitamin B1 (thiamine) refers to water-soluble vitamins.It is necessary for the harmonious flow of the processes of growth and development, as well as the regulation of the cardiovascular, nervous and digestive systems.Vitamin B1 is not deposited in the body, so its stocks must be replenished regularly.In the human body comes from food, thiamine and synthesized using colonic microflora.

Medicinal properties

role of vitamin B1 in the human body is great.First of all, it has a regulating effect on the nervous system.In addition, it is involved in the processes of energy, water and salt, carbohydrate, protein and fat metabolism.Lack of vitamin promotes accumulation in muscle cells of lactic and pyruvic acids which disturb the proper functioni

ng of the nervous and digestive systems.

Vitamin B1 normalizes activity of the brain, improving mental ability, memory and mood.He has a positive effect on the growth and development of the organism, as well as taking an active part in the process of hematopoiesis.Due to its strong antioxidant properties, thiamine reduces harmful effects on the body of various toxins.

difficult to overestimate the importance of Vitamin B1 for hair.With its deficit in the body hair becomes dull, thin and brittle.

daily requirement

daily need for vitamin B1 for an adult male is 1.6-2.5 mg for women - 1,3-2,2 mg, and for the child - 0.51.7 mg.The need for the use of vitamin B1 increases with reinforced physical and mental stress, infections, diabetes, surgical interventions on the body, burns, and other pathological conditions, prolonged treatment with antibiotics, hormonal and sulfanilamidnymi drugs during pregnancy and lactation period.

Deficiency of vitamin B1 in the body

Hypovitaminosis thiamine develops in insufficient intake of the vitamin from food, or if you have problems with his digestion with.This leads to disruption of the normal flow of processes regulated by it, as well as the accumulation of carbohydrates in the body of toxic metabolic products.

People who regularly consume large amounts of alcohol, tea or coffee, are also included in the risk group of vitamin B1 deficiency, since these drinks are destroying it, and removed from the body.

Early symptoms of a lack of thiamine in the body are the following states: memory loss, lack of appetite, constant fatigue, and irritability.Then join them: muscle weakness, lethargy, sleep impairment, feelings of depression, tingling in the legs.

Acute deficiency of vitamin B1 is accompanied by a variety of symptoms:

  • of the cardiovascular system: dyspnea, tachycardia, weakening of cardiac activity, heart pain, swelling;
  • of the nervous system: headache, paresis, peripheral polyneuritis, paralysis;
  • of the digestive system: poor appetite, decreased bowel tone, nausea, abdominal pain, and constipation.

Sources of vitamin B1

The sources of vitamin B1 include products of plant and animal origin:

  • cereals (unprocessed rice, oatmeal, buckwheat);
  • bread and bread from wheat flour;
  • beans and soybeans;
  • broccoli, Brussels sprouts, asparagus;
  • nuts and sunflower seeds;
  • plums, oranges, strawberries, currants, blueberries, rose hips;
  • spinach, parsley, nettles, sorrel, chamomile, mint;
  • raisins and prunes;
  • fish and seafood;
  • meat and meat by-products.

It should be remembered that the amount of vitamin B1 in them is reduced by heat treatment products.

The use of vitamin B1 in ampoules

If insufficient intake of thiamine from the food, and the development of hypovitaminosis prescribe administration of vitamin B1 in ampoules.

Indications for injecting vitamin also become the following ailments:

  • cardiovascular disease: myocarditis, endarteritis, chronic circulatory insufficiency;
  • mental diseases: Alzheimer's disease, dementia, psychosis, depression;
  • neurological diseases: peripheral paralysis, asthenovegetative syndrome, neuritis and polyneuritis;
  • diseases of the digestive system: enterocolitis, ulcers, gastritis, liver cirrhosis, chronic pancreatitis, operated stomach disease.

Veliko vitamin B1 important for hair and skin, so it is widely used in the treatment of many dermatological diseases.Vitamin B1

ampoule administered once per day to adult patients at a dosage of 1 ml, and children - 0.5 ml.The course of treatment with 10-30 injections.Thiamine injections are painful and at the injection site are sometimes formed infiltrates.After injection, rarely develop allergic reactions such as anaphylactic shock, and drug reaction.

Contraindications to the use of vitamin B1

For relative contraindications to the appointment of thiamine include hypertension and other diseases, accompanied by impaired renal excretory function.Vitamin B1 is also contraindicated in patients with drug intolerance in history.

interaction with other drugs

Thiamine passes in the active form in the presence of the body enough magnesium.

Not recommended simultaneous parenteral administration of thiamine with nicotinic acid, streptomycin, penicillin, B6 and B12 vitamins.

Alcohol-sulfonamide drugs and interfere with the absorption of vitamin B1 in the body.

antibiotics, antacid drugs, oral contraceptives and preparations containing sulfur capable of reducing the thiamine level in the body.

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