Gastric ulcer and duodenal ulcer : the risk of cancer

Gastric ulcer and duodenal ulcer : the risk of cancer
symptoms of gastric and duodenal ulcers often resemble symptoms of other diseases or are absent altogether.That is why it is so important timely diagnosis, allowing to avoid complications such as internal bleeding and malignant transformation of cells.

Gastric ulcer and duodenal ulcer: features of the disease

Gastric ulcer and duodenal ulcer in elderly individuals is 10% of all cases of peptic ulcer diseases in Russia.

In these age groups, it has a number of features that are not always pay attention to the patients themselves and their relatives, and it is sometimes difficult to diagnose, reduces the effectiveness of the treatment and the direct impact on the outcome of the disease.

There are two options for the development of gastric and duodenal ulcers in elderly and senile patients who meet with the same frequency:

  • long flowing ulcer that occurred at a young age and since then has periodically escalating;
  • gastric ulcer disease, first emerged in the elderly, which is often a secondary natur
    e, as a concomitant loss in other diseases.

ulcers, arisen at a young age, retains the seasonality of exacerbations (mainly in spring and autumn).This exacerbation occur longer and heavier than in younger years.It is also noted the frequent combination of ulcerative lesions of the stomach and duodenal bulb.

Peptic ulcer that occurred in the elderly, it is called "late ulcer" or "senile ulcer" associated with the presence of age-related changes in the body of the patient, and above all with the development of atherosclerosis, which impairs blood flow to many organs, including the mucousstomach.

This disrupts the natural regeneration and the protective properties of the gastric epithelium.And the presence of concomitant diseases typical of old age, even more worsens the condition of the patient, as they are based also is a violation of the microcirculation in almost all organs and tissues.

Such diseases include:

  • coronary heart disease,
  • hypertension,
  • atherosclerosis of the aorta and its branches,
  • defeat varicose limbs,
  • chronic pyelonephritis,
  • diabetes and others.

Moreover, unlike other types of ulcers, which are mainly caused by Helicobacter, in elderly patients in the 25-30% Helicobacter not detected.

In some cases, "later sores" or asymptomatic with only minor discomfort, which patients often do not pay attention, and peptic ulcer disease is detected by chance during examination on the other complaints and other diseases.

This clinical picture is more typical for ulcers located in the middle and upper parts of the stomach, often with the expressed decrease in acidity, which is not typical for the young and middle-aged persons.

When fibrogastroduodenoscopy and X-ray examination in elderly patients, in spite of the poverty of subjective symptoms, notes the presence of a large (2-3 cm in diameter or more) of ulcer formation in the stomach than in younger patients.

30% of elderly patients have iron deficiency anemia, which is associated with bleeding ulcers due to the fragility of the vascular wall and metabolic disorders in it.

In addition, elderly patients bleeding from the ulcer formation observed in 2 times more often than the young, and is accompanied by a change in the color and structure of the chair (it becomes liquid and black).

This state of medicine is called "melena", but it can be observed not only in gastric ulcer and duodenal ulcer, but also in other diseases, accompanied by bleeding of varying intensity in the digestive organs.

Gastric ulcer and duodenal ulcer: diagnosis

Diagnosis of gastric and duodenal ulcers are very complicated and important process, which depends not only get rid of the patient from the suffering associated with the disease, but the prognosis of the disease and the patient's quality of life, as thisage group are much more prone to cancer.

has now been found that the probability of malignancy existing gastric ulcer does not exceed the probability arose primarily stomach cancer, and malignant transformation of duodenal ulcer - a rare phenomenon.

Unfortunately, not always without a biopsy can not establish a diagnosis of cancer of the stomach, as in many cases, infiltrative-ulcerative form of cancer during the instrumental examinations (x-ray and fibrogastroduodenoscopy) gives a picture of the usual large benign ulcers.

There are a number of reliable clinical signs to suggest the presence of primary ulcer forms of cancer.

These include:

  • rapid (less than one year) the development of the disease;
  • asthenia condition of the patient with progressive weakness, weight loss, significant weakening of appetite;
  • in the patient's blood was accelerated erythrocyte sedimentation rate;
  • iron deficiency anemia;
  • fluoroscopy revealed a number of characteristic features of cancer associated with the presence of a large, asymmetrical ulcer, decreased elasticity of the stomach wall due to infiltrative tumor growth and a number of other symptoms;
  • in probing the stomach is marked "zero" acidity (Akhil) and periodic presence of blood in gastric contents;
  • at fibrogastroduodenoscopy revealed a bleeding ulcer is flat, the bottom of which is covered with clots, ulcers around the marked inflammatory edema, irregular thickening of the mucosa, which is often associated with submucosal tumor growth.At the time of this study shall be required biopsies of different parts of the ulcer, and other areas of the gastric mucosa, this allows to deliver a more accurate diagnosis.

Therefore, patients in middle and old age, and their families should not give up on the survey, appointed doctor, as this will help to make a diagnosis in a timely and appropriate treatment, which will help restore health and prevent the occurrence of serious complications.

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