Glioblastoma : symptoms , treatments , prognosis

Glioblastoma : symptoms , treatments , prognosis
Glioblastoma - a brain tumor.Refers to the so-called glial tumors, ie, abnormal growths formed in glia - supporting tissue of the brain.Most often diagnosed in men aged 40-60 years.

Symptoms Glioblastoma Glioblastoma

clearly manifests itself only when the increases to a considerable size, and is accompanied by a massive cerebral edema.

Symptoms appear just as a result of swelling, then there are certain parts of the brain are under pressure.Tumors can be located in different areas of the brain and the symptoms of the disease depending on this may be different.

Most often, patients and their relatives are beginning to sound the alarm when suddenly manifest speech and motor symptoms.If the tumor touches the motor cortex, then the person may experience disturbances in the limbs - from numbness in the hands and feet before they wear out.

When tumors arise in the areas of speech disorders with the understanding of words, formulating his thoughts, patients may be confused speech and so on.There may als

o be dizziness, seizures.

The most common symptom of glioblastoma - a headache.It occurs in most cases regardless of the tumor, because the swelling of the intracranial pressure rises greatly.However, such non-specific symptom does not allow immediately suspect a tumor, so little information.

Diagnosis is based on computed tomography or magnetic resonance imaging (required with the introduction of a contrast agent into a vein).


Although usually already snapshots experienced neurologist or neurosurgeon can diagnose "glioblastoma" reliably determine the type of tumor is possible only after a biopsy (when a fragment of the tumor in the analysis is taken as a result of surgery or specially conducted interference).

For more information about the tumor and allows you to get emissionnnaya positron tomography (PET).

Glioblastoma: treatment and prognosis

Therapies with glioblastoma is currently limited to the following.

  • neurosurgery .The operation is performed on the brain and allows you to fully or partially remove the tumor.Despite modern techniques of neurosurgery method it is not always applicable.Sometimes the location of the tumor makes the operation unavailable or extremely risky because of the potential damage healthy brain cells in vital areas.
  • Radiotherapy and Radiosurgery .Effects on the tumor cells by ionizing radiation directed.Usually assigned a course of about 30 days.This method does not destroy the tumor, its purpose - to reduce, minimize its activity, does not allow the tumor to grow.Radiosurgery (Technology Gamma Knife and CyberKnife) - less traumatic version of radiation therapy, allows the impact point, without affecting healthy cells, requires a much smaller number of sessions.
  • Chemotherapy .The goal of chemotherapy - also block the growth of tumor and its activity.Used temozolomide substance in the form of tablets.Usually treated with combination chemotherapy with radiation therapy and after supporting courses.Most patients tolerate the drug quite well.
  • Target therapy.Suitable drug Avastin.This drug, which violates the development of tumor blood vessels, and thus inhibits its growth.Avastin is currently used for the treatment of recurrent glioblastoma, and does not apply if the primary tumor is detected.

leading research institutes are developing and testing new drugs for the treatment of glioblastoma, but at the moment no other methods are available.

Throughout the treatment with the diagnosis of glioblastoma patients may also be prescribed the drug dexamethasone.This hormonal agent, allowing to remove a brain edema, which means that most of the symptoms ease.However, this drug causes a number of side effects, so the decision to admit the doctor takes, after weighing all the circumstances.

Unfortunately, despite the use of all these methods, the effectiveness of the treatment of glioblastoma low.The average life span after diagnosis of cancer is 1-2 years (without treatment, death occurs within 2-3 months).

Nevertheless, each case is different.Much depends on the tumor in the brain, how the tumor cells are susceptible to chemotherapy.

Treatment shall appoint a neurosurgeon, radiation therapy specialist chemotherapist depending on the method.

Handle must be in the specialized medical institutions dealing with brain tumors, such institutions exist in many major cities.Suggest a relevant institution is an oncologist in the regional oncologic dispensary, which should also be registered (including for sick leave, processing of disability, if necessary, receive free drugs for chemotherapy).

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