Uric acid is a product of metabolism of purine bases, necessary for normal functioning of the body.Uric acid in the liver mainly produces and output excess uric acid in the kidneys of normal conditions.
the acid is named so because it was first found in the urinary stones and urine.The substance is an organic acid with a small molecule containing a nitrogen, and thus relates to nitrogenous bases, and more specifically, to nitrogenous slag (the final product of purine metabolism reason not used over diversion excretes).
purines themselves included in the nucleic acids in the form of adenine and guanine, purine molecules worked body parts to form the split of uric acid, which for some time is in blood withdrawn until the kidneys.The more
uric acid formed in the body, the longer it is excreted by the kidneys, since their capacity is limited.
concentration of uric acid in the body depends primarily on the amount of dietary purines.They mostly come from animal protein.
No less important is the synthesis of purines by the body, and this fact affects the level of uric acid significantly.
important as the speed with which the purines are utilized by the body, how the body's cells rapidly decompose, releasing purines in the blood plasma, and how well the kidneys ability to excrete uric acid from the body.
In a healthy body uric acid levels in the blood plasma is maintained at a certain level, and this is extremely important, as the increase in uric acid levels (hyperuricemia) can negatively affect health.
uric acid level in men is higher due to the large amount of muscle mass, a heavy physical activity and consumption of large amounts of protein in the diet.
To assess the level of uric acid in blood plasma is necessary to pass the blood chemistry.The results to be valid, it must be eight hours prior to the study to fast, eliminate alcohol and protein-rich foods for three days prior to analysis, to donate blood is strictly on an empty stomach.
in plasma uric acid levels examined in conjunction with other biochemical parameters, the result usually becomes known for the next day.
Increased uric acid levels in plasma is called hyperuricemia.Such a condition occurs when heavy physical labor in connection with the expenditure of large amounts of protein, when taking alcohol (especially red wine), after prolonged starvation, abuse of fat and carbohydrate foods, obesity, nutritional origin.
Increased levels of uric acid may be a symptom of such pathologies as acute infections such as scarlet fever or pneumonia, tuberculosis or cancer.Increases the level of uric acid may be in anemia, especially with a deficiency of vitamin B12 is, eczema, diabetes, psoriasis, or urticaria.
Increased levels of uric acid may be a symptom of kidney disease, a sign of acidification of the blood (metabolic acidosis), alcohol poisoning or toxemia of pregnancy.
Stable increase of uric acid level is the main symptom of gout or gouty arthritis.
for gout is characterized by a combination of increased production of uric acid, while its delayed release.The reaction of uric acid with sodium ions, always present in the body, the crystalline salts are formed - urate.They can produce kidney stones, salt deposits in the joints and the subcutaneous tissue.This disrupts the normal functioning of the organs and cause chronic inflammation and pain.
First of all, at an elevated level of uric acid is necessary to observe a special diet with a decrease in the diet of protein (meat and offal, meat broths and canned food, chocolate and coffee, bean and alcohol).
Often some dietary interventions and gradual weight loss is enough to uric acid levels to normal.To reduce uric acid levels should regularly eat dairy products and milk, lean meat and fish, fruit and vegetables, juices, broth hips and bran.
for active excretion of uric acid from the body is necessary to drink plenty of fluids - two to three liters of clean water, diluted juices, fruit drinks, fruit compotes, lemon juice.
In the case of serious deviations in the level of uric acid is recommended to take special drugs that reduce uric acid levels, - diuretics, drugs that reduce levels of uric acid in the body (allopurinol), drugs to prevent (colchicine).
not less effective and folk remedies to remove uric acid - a decoction bilberry leaf, birch buds, nettle.
All drugs are used only under medical supervision with regular measurements of the levels of uric acid in the blood and urine.
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