Hypertrophic pulmonary osteoarthropathy (Marie's disease - Bamberger) -changes of bones and joints, arising under the influence of toxic effects on bone tumor and / or chronic inflammatory factors.
At the heart of hypertrophic osteoarthropathy, one manifestation of which is the deformation of the fingers in the form of so-called "drumsticks" is a chronic toxic effects of tumor and / or chronic inflammatory factors, as well as the disruption of the autonomic nervous system is always available for severe chronicdiseases.
In the soft tissue of nail phalanges marked edema, increased production of collagen, fibrosis, and spasm of the small peripheral vessels.This leads to a decrease in bone density of nail phalanges, and sometimes middle phalanges, combined with irritation of the periosteum and Response formation periosteal layers.
At the same time marked symptoms of synovitis (inflammation and proliferation of synovial joints), as well as the accumulation of a small amount of effusion in interphalangeal, at least - in the knee, ankle wrist and elbow joints.
If arthropathy occurs on the background of tumor lesions in the blood has accelerated erythrocyte sedimentation rate, leukocytosis, in the synovial fluid is only a small leukocytosis.The rest - the changes specific to the underlying disease.
radiologically determined only small periosteal (periosteal) layers with a long-term chronic disease, ultrasonography of the joints can be detected a slight accumulation of intra-articular fluid.
disease most often symptomatic, anti-inflammatory treatment of joints.Thus, unlike metastatic lesions, such treatment can be effective, accompanied by a decrease of pain and edema.
In cases where surgery is performed lung disease (for cancer, abscess, or bronchiectasis), "drumsticks" and periosteal layers decrease effusion disappears in the joints.
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