What is Cushing's syndrome

What is Cushing
Cushing's syndrome if too much of the hormone.

Cushing's syndrome (hypercortisolism, syndrome Cushing's) - a disease associated with excess cortisol release.Women suffer from it about 10 times more often than men.

What is Cushing's syndrome

Syndrome Cushing's, also called hypercortisolism or syndrome Cushing's (both doctors at various times described the characteristic signs of the disease) - a collection of pathological changes in the human body as a result of overproduction of adrenal kortikosterodidnyh hormones, or after long-term use of corticosteroids drugsin particular, the hormone cortisol.The cause of the syndrome, doctors now associated with dysfunction of the pituitary gland and the hypothalamus, which is known to be closely associated with the adrenal glands.

addition to Cushing's syndrome and the disease exists with the same name.The fact that he's syndrome - a broader concept that includes any pathological condition associated with an excess of cortisol release.Women are sick about th

ese diseases B10 times more often than men.

¬ęcushingoid people¬Ľ

Signs sindoma Cushing:

  • Obesity with the distribution of fat on the abdomen, chest, face and back in the form of a fatty hump (cushingoid obesity type) in combination with a thin transparent skin on the back of his hand.
  • cyanosis face (purple-red skin).
  • Atrophic decrease in the volume of muscles, especially the gluteal muscles and the anterior abdominal wall, and later - the occurrence of hernias "linea alba".
  • thin skin with vascular mesh and "marble" spots.
  • striae in the skin.
  • rash on the face and body of the type "acne."
  • Sometimes dark spots on the face and body.
  • in 90% of patients develop osteoporosis (loss of bone mineral density), which implies their frequent fractures, scoliosis develops over time.
  • Disorders of the heart muscle.
  • unstable nervous system, frequent changes of mood.
  • A small percentage of patients develop steroid diabetes with a healthy pancreas.
  • hirsutism (hairiness of the body and face), the failure of the menstrual cycle in women.

Treatment of Cushing's syndrome

The disease is diagnosed by their appearance, and then - on the level of cortisol in urine and serum.Next, doctors perform a number of specific studies to determine the causes of this condition, such as an MRI for the detection of tumors in the adrenal glands or the pituitary gland, etc.

treatment involves usually several types of therapy.Prescribers lowering steroidogenesis.Another way - with help of the impact of radiation therapy on the pituitary gland to reduce the production of adrenocorticotropic hormone, employee incentive for increased production of cortisol.In the case of tumors of the pituitary or adrenal glands, they are removed.In complicated cases, the running possible surgical removal of the adrenal gland, followed by lifelong intake of corticosteroid hormones.

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