Anemia : Focus - iron

According to WHO, about one billion people on earth suffer iron deficiency states of varying severity.

Iron or hypochromic anemia - a common phenomenon, constituting 80% of all anemias.Most often it occurs in women, as well as develops due to an absolute decrease in iron stores in the body.

Iron or hypochromic anemia - a common phenomenon, constituting 80% of all anemias.Most often it occurs in women, as well as develops due to an absolute decrease in iron stores in the body.

The two main factors that impact on its appearance, it is, as a rule, chronic blood loss and insufficient intake of iron in the body.However, even at normal levels of hemoglobin iron deficiency might be present.

body

Iron Iron - an important trace element of any living organism, the main active component of hemoglobin.From the content and type of iron consumed in the diet it depends largely on the prevalence of iron deficiency among the population in a given region.In the human body (and mammals as well) is contained in t

he cells and extracellular spaces of the depot.About 70% of the total iron in the iron body is cellular, which is involved in the exchange and the inner part of hemoglobin and other heme-containing compounds (myoglobin, enzymes).

Free plasma iron and iron-whey proteins such as transferrin, lactoferrin, are extracellular and trace element involved in the transport of iron.

deposited body iron stores in the liver, spleen and muscles.In case of lack of cellular iron depot is included in the metabolic processes.

And where it only takes? ..

mainly iron ingested with food is absorbed in the duodenum and the early jejunum.If necessary, it is transferred to the transport protein transferrin to the bone marrow (to "recharge" young red blood cells) in the liver (to restock).Iron absorption in the gastrointestinal tract is limited and controlled by its concentration in plasma.Generally, healthy people in the body is kept relatively constant supply of iron, which is supported by the regulation of suction.In other words, the body is designed so that the iron does not suck more than they should.This - a necessary measure to protect the organism from "overdose", when the iron content is 20 g (norm - 1.3 g), there are signs of liver damage, heart, endocrine system.If iron stores in the blood and filled it enough, it remains in the intestinal cells and is excreted in the feces.

to iron assimilated requires ascorbic acid and B vitamins - B3, B6, B12, folic acid.Lack of protein in the diet, as well as an excess of fat and calcium (milk, curd, cheese) reduce iron absorption.The average daily 10 mg iron absorbed.

Symptoms of anemia can be mild to suffer all his life and did not know about it, because it takes virtually no symptoms.As it progresses, patients begin to complain of fatigue, weakness, dizziness, irritability, headaches, shortness of breath, tachycardia, ie, go to the doctor with moderate to severe anemia.If the disease lasts for years, on the exterior of a person "falls print" anemia: flabby skin is dry, hard, bristly hair, brittle, thinning nails, cracks in the corners of the mouth.Quite often in these patients occurs taste perversion: the constant desire to chew chalk, limestone, clay, coal, paper, smell kerosene or drop to the exhaust pipe of the car.

Treatment of iron deficiency anemia in adult

solve the problem of iron deficiency anemia should be to establish and eliminate the cause of bleeding.It is the cause of chronic iron deficiency anemia constant source of bleeding (eg, vascular tumors, tumors of the gastrointestinal tract) eliminated most surgically.The syndrome of malabsorption combined treatment used enzyme preparations.Patients with urgent conditions (in the case of a large loss of blood, and only for health reasons) transfused packed red blood cells.However, often the body adapts to low rates of hemoglobin, and these patients are shown iron supplements.

Because the absorption of iron from food is limited, to restore its reserves diet alone is impossible, especially in anemia of moderate and severe.

Diet.She - primary prevention

When iron deficiency vegetarian diet is not possible, because even as a preventive measure in the diet must contain a sufficient amount of animal protein, iron-containing foods (beef, veal, liver, beans, cottage cheese).Other most important sources of iron - egg yolks, buckwheat, rye bread, green leafy vegetables and nuts.It must be remembered that milk and other dairy products to limit the absorption of iron, so the adult daily consumption of milk should be reduced (up to two cups) and not to use the two hours before iron supplementation.

Careful attention to your diet is necessary for patients from the so-called risk groups: patients with malabsorption syndrome, with heavy uterine bleeding (polimenoree), as well as permanent donors, pregnant women.

iron preparations should be used strictly under the control of the blood picture and saying "a lot - not a little" in this case does not apply.Excess iron in the body can cause serious harm, such as the liver and podzhelulochnoy iron and eliminate it harder than disadvantage.

Secondary prevention

After treatment with iron preparations is completed, shows the secondary prevention of iron deficiency anemia: a therapeutic dose of the drug received reduced to prophylactic.If the level of hemoglobin and serum iron concentration is normalized, the control of these parameters is carried out every month for six months.Then, in the absence of clinical signs of anemia control tests carried out once a year.

Latest Blog Post

Cystitis spring : how to avoid relapse
August 12, 2017

This year the spring was unusually snowy and cold.The body yearned for the sun and vitamins, immunity decreases, which means that chronic diseas...

Fabry disease : it
August 12, 2017

Fabry disease - a rare genetic disease that results in the absence of the enzyme that breaks down lipids.The disease could negatively affect the...

10 interesting facts about the human vision
August 12, 2017

vision - one of the five senses available to man.For centuries, scientists have studied the organ of vision and the process that allows us to se...