Alzheimer's disease can be predicted by the size of the brain

Scientists say that the size of certain areas of the cerebral cortex can judge the likelihood of developing Alzheimer's disease even in people who do not experience any problems with memory.

Measurement of brain size

In a study published in the journal Neurology, researchers from the University of Pennsylvania used data from brain scans to measure the thickness of certain areas of the cortex in 159 people who did not have symptoms of dementia.The average age of study participants was 76 years.Measured sections of bark were selected on the basis of previous studies, which showed a decrease in certain parts of the brain in Alzheimer's patients.

In 19 of the 159 persons risk of developing Alzheimer's disease was considered high because of the smaller areas of the cerebral cortex, subject to destruction in the development of Alzheimer's disease.At 116 risk was secondary and even at 24 - low.

in the diagnosis of Alzheimer's size matters

At the beginning of the study and over the next three years, the

study participants were also measuring memory status, ability to solve problems, make plans, and the ability to focus on specific tasks.In 21% of those with a high risk of developing Alzheimer's disease for three years there was a decline in cognitive functions of the brain, compared with 7% among participants with average risk indicators and lack thereof among participants with low probability of developing Alzheimer's disease.

In addition, the study found that 60% of those with a high risk of Alzheimer's disease was also increased levels of proteins associated with the disease, in the cerebrospinal fluid, which is also a marker of Alzheimer's disease.Thus, participants with moderate risk changes in protein level was detected in only 36% and with low risk - 19%.

Thus, the measurement using the magnetic resonance imaging of the brain sizes destructible Alzheimer's perspective may help in the early diagnosis of the disease even in the absence of symptoms and disorders caused by the disease.

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