chronic helicobacter infection weakens the natural defenses of the gastric mucosa and duodenum against the aggressive action of hydrochloric acid.This, in turn, contributes to ulceration of the mucous.
chronic helicobacter infection weakens the natural defenses of the gastric mucosa and duodenum against the aggressive action of hydrochloric acid.This, in turn, contributes to ulceration of the mucous.So how to treat Helicobacter?
for many years to suppress gastric acid secretion, the prevention and treatment of peptic ulcer disease has been successfully used a number of drugs.These include
Despite the therapeutic effect, these drugs do not allow to achieve eradication, that is the complete elimination of the bacteria Helicobacter pylori from the stomach.As a result, after the abolition of drugs ulcer recurs fairly quickly.Consequently, for the prevention of exacerbations and complications, such as bleeding, perforation of the stomach and a violation of patency, medication must be taken for years.
Eradication of H. pylori infection, in turn, allows you to successfully control the ulcer and prevent its worsening even after discontinuation of anti-ulcer drugs.
proved that the treatment of Helicobacter pylori is an important component of the treatment of rare lymphocytic tumor of the stomach called MALT-lymphoma.
However, despite the clear benefits of eradication of H. pylori infection for the patient, not all doctors have resorted to antibiotic treatment, and approaches to the treatment itself is very contradictory.
How to treat Helicobacter most effectively?Eliminating Helicobacter pylori from the stomach is for the doctor a challenge because bacteria can develop resistance to the most common antibiotics.Therefore, for successful eradication requires the use of two or more antibacterial agents (including clarithromycin or metronidazole) in combination with a proton pump blockers, and / or bismuth drugs that have proven effect on Helicobacter pylori.However, it should be noted that despite all the difficulties impact on Helicobacter pylori, the treatment it quite successfully.Such combinations
relieve the patients from the infection in 70-90% of cases.However, it proved that the microorganisms often become resistant, that is resistant to clarithromycin, especially if the patient has previously received the antibiotic or its analogues (drugs macrolide).
Drug resistance can develop and metronidazole.In such cases, doctors have to make other treatment regimens for Helicobacter pylori.So the answer to the question of how to treat Helicobacter not easy to find.
In some cases, after a course of antibiotics the doctor prescribes specific tests that allow to confirm the success of the therapy.These include the urea breath test or stool antigen test for Helicobacter pylori.Research is especially important for those patients in whom the infection was accompanied by complications such as bleeding or perforation of the mucous membrane of the stomach or duodenum 12.
Endoscopic examination and blood tests for antibodies, which are used for the purpose of diagnosis of infection, are not suitable for confirming the effectiveness of treatment.
If eradication of Helicobacter pylori was not successful, then the doctor prescribes re-treatment, often with a change of dosage scheme.
According to generally accepted guidelines, treatment should be performed in all patients, if helicobacter infection is accompanied by the appearance of ulcers on the mucosa.The goals of therapy is to eliminate the infection, the healing of ulcers and prevention of exacerbations.
also eradication of infection is required for MALT-lymphoma.It is proved that after the successful elimination of Helicobacter pylori tumor regresses quickly and usually does not appear again.
standard guidelines do not provide for eradication treatment in the absence of ulcer disease or gastric MALT-lymphoma.In such cases, the doctor must carefully weigh the possible benefits of treatment and the risk of side effects with use of antibiotics.
On the other hand it is known that Helicobacter pylori infection promotes atrophic gastritis - chronic inflammation which leads to the atrophy, i.e. the gradual destruction of the gastric mucosa.This condition is associated with the restructuring of the stomach lining and predispose to the occurrence of gastric cancer.
Elimination of microorganisms from the stomach prevents the development of atrophic states.This is why some doctors recommend to treat H. pylori infection and the absence of clear symptoms or endoscopic signs of ulcers.
Many experts believe that the infection of the gastrointestinal tract Helicobacter pylori also causes indigestion, then there are indigestion, heartburn, vomiting, a violation of the chair and others. Thus, eradication of infection may benefit in such cases.
Genetic studies have identified several strains (types) of Helicobacter pylori.However, some bacteria cause ulcers and stomach cancer much more often than others.The results of further scientific studies will help physicians select patients more clearly, which will require eradication treatment.Here are the main ways of options on how to treat Helicobacter.
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